Background: Multiple antibacterial agents
have been mixed and used as an intracanal medicament
to eliminate E.faecalis, which has been most frequently
identified in the cases of failed root canal treatment and
periapical lesions. This study is aimed at using newer
intracanal medicament Nitrofurantoin and Ozonated oil
plus calcium hydroxide against E.faecalis bacteria. Aim:
To compare the antimicrobial efficacy of newer
intracanal medicament Nitrofurantoin and Ozonated oil
plus calcium hydroxide on E.faecalis - an in vitro study.
Materials and methodology: Thirty extracted premolars
were collected and instrumented with rotary files (size
25-4% taper). Then, root canals were contaminated with
a bacterial solution of E.faecalis for 21 days, and divided
into two groups. In the root canals of group A
nitrofurantoin intracanal medicament was placed and in
group B ozonated oil plus calcium hydroxide intracanal
medicament was placed and sealed for 7 days. Then on
the 8th day, the contaminated root canals were flushed
with normal saline to remove the medicament. To
evaluate the degree of contamination, the specimens of
the dentin chips from the full length of the root canal
were harvested using a sterile rotary instrument (size 25-
6% taper) and placed in BHI broth and same were
subjected for dilution and colony count after 24 hours.
Data was recorded and subjected to statistical analysis.
Results and conclusion: within the limits of the study,
Nitrofurantoin showed greater antibacterial efficacy on
E.faecalis when compared to the mixture of Ozonated oil
plus calcium hydroxide as an intracanal medicament.
Keywords :
Nitrofurantoin, Ozonated oil, Calcium hydroxide, E.faecalis, antibacterial efficacy