Comparative Evaluation of Chlorhexidine and Hydrogen Peroxide Mouth Wash among Patients with Gingivitis


Authors : Dr. Shamila Shetty K; Dr. Misha Rose Mathew; Devika M; Arunima S Kannan

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/40LYWCh

DOI : https://doi.org/10.5281/zenodo.8099503

Abstract : Goals and Purpose: The purpose of this study was to compare the effectiveness of chlorhexidine (CHX) and hydrogen peroxide (H2O2) mouthwash on individuals with chronic periodontitis. Materials and Procedures A total of 51 patients with advanced gingivitis were selected. Three groups of subjects were created and distributed evenly. SRP and 0.2% CHX gluconate mouthwash were administered to Group I twice daily for 14 days. Scaling and root planning (SRP) was administered to patients in Group II in addition to 1.5% H2O2 mouthwash over a 14-day period, while SRP was administered to patients in Group III. Patients in all groups had their gingival index and plaque index measured on days 0, 7, and 14, respectively. Using Student's paired and unpaired 't' and oneway ANOVA (Analysis of Variance) tests, the statistical analysis for comparisons between and within groups was carried out. Statistics were considered significant at P values less than 0.05. R (version 4.1.2) is used to conduct the complete analysis. Results: The gingival plaque index was significantly reduced by both CHX gluconate and H2O2 mouthwashes, but not as much as in the control group. Combining mouthwash with 0.2% CHX gluconate was an efficient treatment for participants with severe SRP in lowering the gingival index and plaque index. Conclusion: CHX gluconate was found to be more effective than H2O2 at reducing plaque and gingival index.

Keywords : Chlorhexidine gluconate, gingivitis, hydrogen peroxide

Goals and Purpose: The purpose of this study was to compare the effectiveness of chlorhexidine (CHX) and hydrogen peroxide (H2O2) mouthwash on individuals with chronic periodontitis. Materials and Procedures A total of 51 patients with advanced gingivitis were selected. Three groups of subjects were created and distributed evenly. SRP and 0.2% CHX gluconate mouthwash were administered to Group I twice daily for 14 days. Scaling and root planning (SRP) was administered to patients in Group II in addition to 1.5% H2O2 mouthwash over a 14-day period, while SRP was administered to patients in Group III. Patients in all groups had their gingival index and plaque index measured on days 0, 7, and 14, respectively. Using Student's paired and unpaired 't' and oneway ANOVA (Analysis of Variance) tests, the statistical analysis for comparisons between and within groups was carried out. Statistics were considered significant at P values less than 0.05. R (version 4.1.2) is used to conduct the complete analysis. Results: The gingival plaque index was significantly reduced by both CHX gluconate and H2O2 mouthwashes, but not as much as in the control group. Combining mouthwash with 0.2% CHX gluconate was an efficient treatment for participants with severe SRP in lowering the gingival index and plaque index. Conclusion: CHX gluconate was found to be more effective than H2O2 at reducing plaque and gingival index.

Keywords : Chlorhexidine gluconate, gingivitis, hydrogen peroxide

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