Authors : A Amri; K Essahli; A Hinda; D Talhik; H Zahid

Volume/Issue : Volume 10 - 2025, Issue 3 - March

Google Scholar : https://tinyurl.com/5xc99yz2

Scribd : https://tinyurl.com/bdepb2yk

DOI : https://doi.org/10.38124/ijisrt/25mar564

Google Scholar

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Note : Google Scholar may take 15 to 20 days to display the article.

Abstract : Introduction Myeloproliferative syndromes, including conditions such as chronic myelogenous leukemia, essential thrombocythemia, polycythemia vera, and primary myelofibrosis, are characterized by the excessive production of stem cells in the bone marrow. This study aims to describe the epidemiological and cytological profile of these syndromes at the Mohammed V Military Instruction Hospital in Rabat. Materials and Methods: The study, conducted over one year, was observational, cross-sectional, descriptive, and analytical. Data were collected from the hematology laboratory registers, and statistical analysis was performed using IBM SPSS Statistics 19 and Microsoft Excel 2019.  Results Fourteen suspected cases of myeloproliferative syndrome were identified, with a male predominance (69.2%) and an average age of 57.75 years for CML, 61.75 years for PMF, 73 years for PV, and 81 years for ET. The main presentations included leukocytosis for CML, thrombocytosis for PV, and multilineage dysplasia for PMF.  Conclusion Our study at HMIMV Rabat highlights the importance of a multidisciplinary approach to myeloproliferative syndromes. Advanced hematological and cytological analysis methods were crucial for confirming the diagnosis and guiding treatment.

Keywords : Myeloproliferative Syndromes, Hematopathy, Diagnosis.

References :

1. Arber DA, Orazi A, Hasserjian R, et al , Le Beau MM, Bloomfield, Vardiman JW. The 2016 revision to the World HealthOrganization classification of myeloidneoplasms and acute leukemia. Blood. 2016;127(20):2391–2405
2. Fowlkes, S., Murray, C., Fulford, A., et al. (2018). Néoplasies myéloprolifératives–Partie 1: survol du diagnostic et du traitement des NMP «classiques». Canadian OnCOlOgy nursing JOurnal, 28(4), 269.
3. Corberand JX. Syndrome myéloproliferatifs : présentation clinique et aspect biologique. Feuillet de biologie 237 (2000), p 5-18.
4. Chakour M, Boumhil L, Maleb A, et al. LES SYNDROMES MYÉLOPROLIFÉRATIFS. Maroc Méd [Internet]. 2010 [cité 4 juill 2024] ;32(2).
5. Leguay T, Mahon FX. Leucémie myéloïde chronique. Hématologie 2005, 2 : 187–205.