The branded drugs are the patent protected.The branded drugs are marketed under a unique proprietary name given by the company.The generic drugs are off the patent.The generic drugs are marketed under the generic name of the drugs . The branded drugs are costly where as the generic drugs are cheap.There is no big difference between the generic and branded drugs.we taken fluconazole as for study purpose.The fluconazole tablet contain NLT 90.0%and NMT 110.0% of the labelled amount of the fluconazole.The fluconazole is the antifungal medication used for a number of the fungal infection eg.. candidiasis, blastomycosis, coccidiodomycosis etc.The boiling point is 579.8°c.The plasma half life of fluconazole is approximately 30hours. The dissolution time of fluconazole is 30 min.Fluconazole is available as either an oral or intravenous form and oral administration has a bioavailability of approximately 90%relative to intravenous administration.

Keywords : Fluconazole, Dissolution time, Disintegration, Tablet