Comprehensive Investigation of Pyrimidine Synthesis, Reactions, and Biological Activity


Authors : Fawzy Abdelshafy; Mashael M. Barqi; Ambreen Ashar; Maria Javed; Ayesha Kanwal; Mohamed R. Eletmany

Volume/Issue : Volume 8 - 2023, Issue 10 - October

Google Scholar : https://tinyurl.com/39vd9yyh

Scribd : https://tinyurl.com/363s69wh

DOI : https://doi.org/10.5281/zenodo.10049953

Abstract : Researchers have devoted much attention to the study of the chemistry of pyrimidines due to their broad range of pharmaceutical activities. The important role of pyrimidines in the field of drugs is derived from the fact that they are present in genetic material of cells. In this review, we discuss various synthetic methods for pyrimidine derivatives, as well as their various categories of reactions and biological activities as illustrated by research conducted in recent years.

Keywords : Pyrimidine; Pharmaceutical Activities; Drugs.

Researchers have devoted much attention to the study of the chemistry of pyrimidines due to their broad range of pharmaceutical activities. The important role of pyrimidines in the field of drugs is derived from the fact that they are present in genetic material of cells. In this review, we discuss various synthetic methods for pyrimidine derivatives, as well as their various categories of reactions and biological activities as illustrated by research conducted in recent years.

Keywords : Pyrimidine; Pharmaceutical Activities; Drugs.

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