Authors : Dr. Dina Houjjaj; Dr. Sara Mouhmouh; Dr. Sara Yasyn; Dr. Fatima Zahra Azraq; Amal Benbella; Bouchaib Allae Eddine; Abdelhai Adibe Filali; Mohammed Hassan Alami; Rachid Bezad

Volume/Issue : Volume 11 - 2026, Issue 5 - May

Google Scholar : https://tinyurl.com/yc7tv2r8

Scribd : https://tinyurl.com/4346v8s5

DOI : https://doi.org/10.38124/ijisrt/26May1535

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Abstract : Introduction: Congenital aplasia cutis (CAC) is a rare malformation characterized by the absence of skin at birth. Its association with congenital anonychia and hemangiomas represents an even more exceptional entity.  Case Report: We report the case of a female newborn, weighing 3,670 g, delivered vaginally at 39 weeks of gestation with an Apgar score of 10, born to a 35-year-old multiparous mother (G5P4) with no notable personal or family history, no consanguinity, and no exposure to medications or medicinal plants. Clinical examination at birth revealed multifocal aplasia cutis lesions (trunk and dorsal region), complete anonychia of the toes, and a large vascular formation consistent with a hemangioma on the right upper limb.  Discussion: CAC may occur in the context of complex syndromes (Adams-Oliver, Bart, Johansson-Blizzard). The association with anonychia and hemangiomas suggests Adams-Oliver syndrome, which requires rigorous multidisciplinary management.  Conclusion: This case illustrates the importance of a precise clinical description and a comprehensive etiological workup in the neonatal period for any newborn presenting with aplasia cutis, in order to establish a prognosis and guide the family.

Keywords : Aplasia Cutis Congenita; Anonychia; Hemangioma; Adams-Oliver Syndrome; Newborn.

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