Conn’s Syndrome in a Male Adult with Uncontrolled Hypertension; A Case Report

Authors : Taiwo Folasade; Durotoluwa M; Adedokun T; Ajanya O; Nnamonu A; Oshaju H; Nwankwo A; Abdullahi B; Ojji B; Alfa J; Odili N

Volume/Issue : Volume 6 - 2021, Issue 4 - April

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Adrenal hyperplasia is a rare cause of secondary hypertension1 . Our index case Is 54 year old community health extension worker, known hypertensive of 20 years who presented on account of uncontrolled hypertension with background family history of hypertension in both parents and siblings. Methods: we retrieved the case file of the patient from UATH Data and Record unit. Results: Patient blood pressure during the period of evaluation was persistently elevated with mean blood pressure of 185/115 + 10mmHg while on triple antihypertensive. Biochemistry result showed severe hypokalaemia of 2.2mmol/l, aldosterone level was markedly elevated with value of 33.90ng/dl, serum renin level of 0.68ng/dl and aldosterone renin-ratio is 49.9, abdominal CT showed features of bulky adrenal gland worse on the left. Conclusion: Clinical impression of Conn’s syndrome was made based on the above findings. Patient was placed on spironolactone- an aldosterone antagonist with other antihypertensive. Patient symptoms resolved, his blood pressure became normal and the electrolyte abnormalities corrected at the 6-8weeks of treatment

Keywords : Adrenal Gland, Conn’s Syndrome, Hypertension, Hypokalaemia


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