Copper Nanoparticles Phytofabrication by Utilizing Brassica oleracea var. gemmifera and Exploring their Potential as Antioxidant and Antibacterial Agents


Authors : M Elanchezhian; Boggula Vamsi Krishna; Upadhyayula Venkata Ramana Maruthi Kumar; Sudhakar Poda

Volume/Issue : Volume 8 - 2023, Issue 10 - October

Google Scholar : https://tinyurl.com/mryn6999

Scribd : https://tinyurl.com/4rfukaf5

DOI : https://doi.org/10.5281/zenodo.10074878

Abstract : The study aimed to synthesize copper nanoparticles (CuNPs) using Brassica oleracea var. gemmifera extract (BOE) and investigate their antioxidant and antibacterial properties. The BOE- mediated CuNPs (BOE-CuNPs) were successfully synthesized utilizing reducing and stabilizing properties of B. oleracea var. gemmifera extract. The nanotechnology features showed that BOE-CuNPs were nano in size (106.59 ± 4.77 nm), slightly agglomerated, stable (-12.41 ± 1.88 mV), and made up of mainly copper. The green synthesized BOE-CuNPs have potential antioxidant features and have EC50 values (concentration essential to inhibit 50% of free radicals) of 334.09 ± 17.70 μg/mL and 361.43 ± 12.91 μg/mL in DPPH and ABTS free radical scavenging activity, correspondingly, and could be useful in treating oxidative-stress-mediated conditions. Also, as-synthesized BOE-CuNPs have potential antibacterial activity and showed the highest antibacterial activity against Escherichia coli – MTCC 41 and Listeria monocytogenes – MTCC 657, and could be useful as an antibacterial representative in the biomedical field. However, to utilize BOE-CuNPs, an in- detailed functional and toxicological profile of BOE- CuNPs needs to be performed.

Keywords : Copper Nanoparticles, Brassica oleracea var. gemmifera, Green Synthesis, Antioxidant Activity, Antibacterial Activity.

The study aimed to synthesize copper nanoparticles (CuNPs) using Brassica oleracea var. gemmifera extract (BOE) and investigate their antioxidant and antibacterial properties. The BOE- mediated CuNPs (BOE-CuNPs) were successfully synthesized utilizing reducing and stabilizing properties of B. oleracea var. gemmifera extract. The nanotechnology features showed that BOE-CuNPs were nano in size (106.59 ± 4.77 nm), slightly agglomerated, stable (-12.41 ± 1.88 mV), and made up of mainly copper. The green synthesized BOE-CuNPs have potential antioxidant features and have EC50 values (concentration essential to inhibit 50% of free radicals) of 334.09 ± 17.70 μg/mL and 361.43 ± 12.91 μg/mL in DPPH and ABTS free radical scavenging activity, correspondingly, and could be useful in treating oxidative-stress-mediated conditions. Also, as-synthesized BOE-CuNPs have potential antibacterial activity and showed the highest antibacterial activity against Escherichia coli – MTCC 41 and Listeria monocytogenes – MTCC 657, and could be useful as an antibacterial representative in the biomedical field. However, to utilize BOE-CuNPs, an in- detailed functional and toxicological profile of BOE- CuNPs needs to be performed.

Keywords : Copper Nanoparticles, Brassica oleracea var. gemmifera, Green Synthesis, Antioxidant Activity, Antibacterial Activity.

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe