A new coronavirus strain known as Severe
Acute Respiratory Syndrome Coronavirus (SARS-CoV-2)
is responsible for the global pandemic that began in 2019
and continues to plague the planet. The disease's
epidemiological features in Africa are different from those
in other continents. The aim of this study is to establish
the relationship that exists between COVID-19 patients'
demographics, symptoms, comorbidities and the risk of
COVID-19-related mortality in the Gambia between April
4, 2020 and March 31, 2021.
Design. The researchers studied 3547 confirmed positive
COVID-19 anonymized cases derived from the DHIS2
database in a retrospective cohort analysis. The factors
analyzed include the demographics of the cases, their
signs and symptoms, and their comorbidities. The main
outcome of interest was death with COVID-19.
Results. For the time period under consideration, 3547
anonymized positive COVID-19 events were analyzed.
The fatality rate was 0.56%, with a median age of 60.5
(50–71) for those who died with COVID-19 and the pvalue < 0.001. Males are more likely to develop the disease
and die from it (63.1% and 85%, respectively). Except for
age and sex (both p < 0.05), all factors studied were
considered to be statistically insignificantly correlated
with the outcome. Cough (11.1%), fever (9.4%), and
shortness of breath (4.3%) were the most common signs
and symptoms identified by the cases. 4.62 % and 18.1 %
of all confirmed positive COVID-19 cases, respectively,
had one of the comorbidities and reported one of the
COVID-19 signs and symptoms in TABLE 1. There was
no statistically significant association between the signs
and symptoms or the comorbidities and the outcome.
CVD (2.7%), diabetes (1.5%), and ARDS (0.8%) and
CLD (0.4%) were the most often identified comorbidities
among the cases. Symptoms and comorbidities were
reported more often by survivors than those who died
with COVID-19. Age, shortness of breath, and diabetes all
increase the risk of death with COVID-19, as per the
multivariate logistic regression. In this analysis, however,
only age was a significant predictor of mortality with
Interpretation. The findings of our analysis are consistent
with those of the Lusaka cohort, which reported that
advanced age increased mortality with COVID-19, and
that the most common comorbidities were CVD
(hypertension) and diabetes, with a higher proportion of
male COVID-19 cases. To better understand the
characteristics of COVID-19 hospitalized cases in relation
to death with COVID-19, length of hospitalization, and
treatment, further exploratory data analysis is needed
Keywords : COVID-19; Comorbidities; The Gambia; Ministry of Health; Correlation; Prevalence; Mortality.