Authors :
Dr Rambhika Thakur; Dr. Vikas Jindal; Dr Saroj Thakur; Dr. Pavan Kumar Gujjar; Dr. Jyoti Zingade; Dr. Ajay Mahajan
Volume/Issue :
Volume 8 - 2023, Issue 4 - April
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://rb.gy/pbj9b
DOI :
https://doi.org/10.5281/zenodo.8281141
Abstract :
Background: An acute-phase protein found in
plasma that reflects a measure of acute phase response to
inflammation is C-reactive protein (CRP). Early detection
of periodontal disease and its prediction can be used by
CRP. There is an association of C-reactive protein with
adverse pregnancy outcomes, including pre-eclampsia
intrauterine growth restrictions, and preterm delivery.
The present study endeavor to evaluate serum C-reactive
protein level in pregnant women with and without
periodontal disease and to compare incidence of pre-term
delivery in pregnant women with and without periodontal
disease .Material and methods This study was undertaken
in 40 pregnant women, divided into 2 equal groups of 20
pregnant women within 22nd weeks of gestation; group I
(study group) with periodontal disease and group II
(control group) without periodontal disease. Blood samples
were taken for estimation of C-reactive protein levels from
both the groups within 22nd weeks of gestation and were
sent for laboratory analysis. CRP levels were determined
using Immuno Turbidometry method on an autoanalyzer.
Result It was found that the mean value of CRP levels is
correlated with high incidence of preterm delivery.
Subjects with preterm delivery have high mean CRP
values as compared to subjects with normal delivery.
Conclusion Increased CRP levels in early pregnancy is
associated with periodontal disease in pregnant women. In
healthy normal controls the incidence of preterm delivery
is lesser comparative to pregnant women with periodontal
disease.
Keywords :
C-Reactive Protein, Periodontal Disease, Preterm.
Background: An acute-phase protein found in
plasma that reflects a measure of acute phase response to
inflammation is C-reactive protein (CRP). Early detection
of periodontal disease and its prediction can be used by
CRP. There is an association of C-reactive protein with
adverse pregnancy outcomes, including pre-eclampsia
intrauterine growth restrictions, and preterm delivery.
The present study endeavor to evaluate serum C-reactive
protein level in pregnant women with and without
periodontal disease and to compare incidence of pre-term
delivery in pregnant women with and without periodontal
disease .Material and methods This study was undertaken
in 40 pregnant women, divided into 2 equal groups of 20
pregnant women within 22nd weeks of gestation; group I
(study group) with periodontal disease and group II
(control group) without periodontal disease. Blood samples
were taken for estimation of C-reactive protein levels from
both the groups within 22nd weeks of gestation and were
sent for laboratory analysis. CRP levels were determined
using Immuno Turbidometry method on an autoanalyzer.
Result It was found that the mean value of CRP levels is
correlated with high incidence of preterm delivery.
Subjects with preterm delivery have high mean CRP
values as compared to subjects with normal delivery.
Conclusion Increased CRP levels in early pregnancy is
associated with periodontal disease in pregnant women. In
healthy normal controls the incidence of preterm delivery
is lesser comparative to pregnant women with periodontal
disease.
Keywords :
C-Reactive Protein, Periodontal Disease, Preterm.
