Authors :
Ankita Tiwari; Dr. Suman Ramteke; Neha Shukla
Volume/Issue :
Volume 9 - 2024, Issue 3 - March
Google Scholar :
https://tinyurl.com/26yjkfcx
Scribd :
https://tinyurl.com/7hw8fat2
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24MAR397
Abstract :
Introduction:
The skin is the most important exposed a part of the
body, is crucial in establishing social bonds and defending
against environmental harm. In the present scenario to
look attractive is a primary concern for the growing
population in order to maintain social integrity and well
being. However cell death is a natural process but due to
highly stressful environmental conditions now a day’s
skin aging is a primary concern for dermatologists. In the
present research work we aim to develop a novel anti-
ageing cream for the prevention and treatment of
unnatural skin ageing by utilizing pomegranate seed oil.
Method:
The pomegranate seed oil was purchased from
Amarnath export Bangalore Karnataka. The preparation
of anti-aging cream was accomplished through
conventional method by taking pomegranate seed oil as
an oily phase and stearic acid as an emulsifying agent. The
formulation was optimized by varying the concentration
of aqueous and oily phase.
Result and Discussion:
The pH of the developed cream was found to be 7.2
± 1.2 and viscosity was found to be 5639±2.51cps.
Furthermore the spreadibility of the developed cream was
found to be 26.6 ±0.2 gm*cm/sec. The developed
formulation showed no skin irritation or erythema and
also it was easily washable from skin. The stability study
of the formulation was studied for 3 month at room
temperature (25oC) which suggests high stability as no
indication of cracking, phase separation or any other
visual change was observed. Furthermore the developed
formulation was analyzed through in vivo animal
model(Albino wistar rat) which suggest high
biocompatibility and potential in the management of skin
ageing.
Conclusion:
In conclusion we have developed a novel
pomegranate seed oil based anti-aging cream for the
prevention and treatment of unnatural skin ageing caused
by the vulnerable environmental conditions. The
developed formulation was analyzed through extensive in
vitro and in vivo characterization which proves the
potential of the developed cream in the management of
unnatural skin ageing.
Keywords :
Cosmetology, Pomegranate Seeds Oil, Skin Ageing, Anti-Aging Cream, Animal Model.
Introduction:
The skin is the most important exposed a part of the
body, is crucial in establishing social bonds and defending
against environmental harm. In the present scenario to
look attractive is a primary concern for the growing
population in order to maintain social integrity and well
being. However cell death is a natural process but due to
highly stressful environmental conditions now a day’s
skin aging is a primary concern for dermatologists. In the
present research work we aim to develop a novel anti-
ageing cream for the prevention and treatment of
unnatural skin ageing by utilizing pomegranate seed oil.
Method:
The pomegranate seed oil was purchased from
Amarnath export Bangalore Karnataka. The preparation
of anti-aging cream was accomplished through
conventional method by taking pomegranate seed oil as
an oily phase and stearic acid as an emulsifying agent. The
formulation was optimized by varying the concentration
of aqueous and oily phase.
Result and Discussion:
The pH of the developed cream was found to be 7.2
± 1.2 and viscosity was found to be 5639±2.51cps.
Furthermore the spreadibility of the developed cream was
found to be 26.6 ±0.2 gm*cm/sec. The developed
formulation showed no skin irritation or erythema and
also it was easily washable from skin. The stability study
of the formulation was studied for 3 month at room
temperature (25oC) which suggests high stability as no
indication of cracking, phase separation or any other
visual change was observed. Furthermore the developed
formulation was analyzed through in vivo animal
model(Albino wistar rat) which suggest high
biocompatibility and potential in the management of skin
ageing.
Conclusion:
In conclusion we have developed a novel
pomegranate seed oil based anti-aging cream for the
prevention and treatment of unnatural skin ageing caused
by the vulnerable environmental conditions. The
developed formulation was analyzed through extensive in
vitro and in vivo characterization which proves the
potential of the developed cream in the management of
unnatural skin ageing.
Keywords :
Cosmetology, Pomegranate Seeds Oil, Skin Ageing, Anti-Aging Cream, Animal Model.
