Authors : Sachi

Volume/Issue : Volume 10 - 2025, Issue 1 - January

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Google Scholar : https://tinyurl.com/7r4ehwhb

Scribd : https://tinyurl.com/2s45b9zf

DOI : https://doi.org/10.5281/zenodo.14869989

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Abstract : CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) technology has revolutionized genome editing by providing a versatile and precise tool for genetic modifications. Since its discovery as a bacterial adaptive immune system, CRISPR has evolved into a powerful tool for molecular biology, medicine, agriculture, and biotechnology. This review discusses the fundamental mechanisms underlying CRISPR/Cas systems, the advancements in CRISPR technology, and the innovations that have expanded its capabilities. Additionally, this paper addresses the current challenges and future directions for CRISPR-based research and applications.

Keywords : CRISPR, Genome Editing, Cas9, Base Editing, Prime Editing, RNA Editing, Gene Therapy.

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