Defensins in Periodontics: A Comprehensive Review


Authors : Dr. Dhrittisha Parag; Dr. Sapna Nadiger; Dr. Suchetha Aghanashini; Dr. Darshan Basavaraj Mundinamane; Dr. Apoorva Sokke Mallikarjunappa; Dr. Aditi Gupta; Dr. Medha G Naik; Dr.Susan Isaac

Volume/Issue : Volume 9 - 2024, Issue 9 - September


Google Scholar : https://tinyurl.com/yaf8mp27

Scribd : https://tinyurl.com/3fcrv34x

DOI : https://doi.org/10.38124/ijisrt/IJISRT24SEP922

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Periodontal diseases, such as gingivitis and periodontitis, are inflammatory disorders that impact the tissues supporting the teeth. These diseases are initiated by bacterial plaque biofilms that form on the tooth surface. The host's immune response to this bacterial challenge plays a crucial role in disease progression. Among the various components of the immune system, antimicrobial peptides (AMPs) such as defensins have gained significant attention for their role in maintaining oral health and their potential therapeutic applications in periodontics. This review article explores the biology, function, and therapeutic potential of defensins in periodontal health and disease.

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Periodontal diseases, such as gingivitis and periodontitis, are inflammatory disorders that impact the tissues supporting the teeth. These diseases are initiated by bacterial plaque biofilms that form on the tooth surface. The host's immune response to this bacterial challenge plays a crucial role in disease progression. Among the various components of the immune system, antimicrobial peptides (AMPs) such as defensins have gained significant attention for their role in maintaining oral health and their potential therapeutic applications in periodontics. This review article explores the biology, function, and therapeutic potential of defensins in periodontal health and disease.

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