Authors :
Poonam Rahangdale; Nandini Dani; Mina Patle; Pooja Nandane; Mansi Jain; Prachi Suryavanshi
Volume/Issue :
Volume 9 - 2024, Issue 4 - April
Google Scholar :
https://tinyurl.com/3ysxv2rv
Scribd :
https://tinyurl.com/9bxdu8sy
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24APR1612
Abstract :
Stretch marks (Striae distensae) are visible
lines on the outer skin located usually on abdomen,
breats, thighs. Stretch marks which develop on pregnant
women known as striae gravidarum. Almost 50-90% of
pregnant women may develop striae distensae. It is
caused due to sudden increase in weight during
pregnancy, due to rapid weight gain the collagen fibres
present between dermis and epidermis layer of skin gets
break down and stretch marks appears. Because of
various side effects of synthetic medications, the use of
herbal medications has increased. To avoid side effect, oil
obtained from the leaves of Centella asiatica linn i.e.
Gotukola and the fruits of Prunus armeniaca i.e.
Apricot was incorporated into the formulation stimulates
collagen synthesis by energizing dermal fibroblast and
regenerate the skin cells. The main active ingredient
found in gotukola is triterpenoids (saponin) and Apricot
is glycosides, it increases collagen production in body
and regenerate the skin cells this may help to prevent
new stretch marks from forming as well as help to heal
any existing marks. The objective of the present study
was to developing the cream for the removal of stretch
marks. Creams was prepared by oil-in-water emulsion
by changing the concentration of active ingredients.
Total 3 formulation were prepared among these F3
batch. In this (1.5% and 2%) concentration of oil was
added and some butters were added. The final
formulation shows pH (8.9), No skin irritancy, better
spreadability, consistency and antimicrobial testing.
Keywords :
Centella Asiatica, Prunus Armeniaca, Apricot, Gotukola, Striae Distensae.
Stretch marks (Striae distensae) are visible
lines on the outer skin located usually on abdomen,
breats, thighs. Stretch marks which develop on pregnant
women known as striae gravidarum. Almost 50-90% of
pregnant women may develop striae distensae. It is
caused due to sudden increase in weight during
pregnancy, due to rapid weight gain the collagen fibres
present between dermis and epidermis layer of skin gets
break down and stretch marks appears. Because of
various side effects of synthetic medications, the use of
herbal medications has increased. To avoid side effect, oil
obtained from the leaves of Centella asiatica linn i.e.
Gotukola and the fruits of Prunus armeniaca i.e.
Apricot was incorporated into the formulation stimulates
collagen synthesis by energizing dermal fibroblast and
regenerate the skin cells. The main active ingredient
found in gotukola is triterpenoids (saponin) and Apricot
is glycosides, it increases collagen production in body
and regenerate the skin cells this may help to prevent
new stretch marks from forming as well as help to heal
any existing marks. The objective of the present study
was to developing the cream for the removal of stretch
marks. Creams was prepared by oil-in-water emulsion
by changing the concentration of active ingredients.
Total 3 formulation were prepared among these F3
batch. In this (1.5% and 2%) concentration of oil was
added and some butters were added. The final
formulation shows pH (8.9), No skin irritancy, better
spreadability, consistency and antimicrobial testing.
Keywords :
Centella Asiatica, Prunus Armeniaca, Apricot, Gotukola, Striae Distensae.