Authors : Dr. Arvind Vishnoi; Dr. Jatin G. Bhatt; Dr. Divyang Chavda; Dr. Mihir Dungrani; Dr. Pratick Baisakh

Volume/Issue : Volume 11 - 2026, Issue 3 - March

Google Scholar : https://tinyurl.com/bdyuc5r5

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DOI : https://doi.org/10.38124/ijisrt/26mar1948

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Abstract : Background Hereditary spherocytosis is a congenital disorder predominantly inherited in autosomal dominant pattern. It is characterised by haemolytic anemia which presents as Anemia , Jaundice ,Spleenomegaly and gall stones (pigmented gall stones) . Splenectomy is definitive treatment with laparoscopic approach increasingly preferred but open splenectomy also favoured in selected cases  Case Presentation We present two cases of hereditary spherocytosis managed with two different surgical approaches. A 33-year-old male patient with symptomatic splenomegaly and cholelithiasis underwent combined laparoscopic splenectomy with cholecystectomy, resulting in rapid postoperative recovery. A 47-year-old patient presented with severe anemia, jaundice, and massive splenomegaly who underwent open splenectomy after preoperative optimization. Both patients showed significant clinical and hematological improvement postoperatively.  Conclusion Both approaches laparoscopic and open splenectomy are almost equally effective in managing HS , minimally invasive surgery has advantage of faster recovery, while open splenectomy remains a safe and effective option in cases of massive splenomegaly or resource limitations . Individualised surgical planning is essential for best outcomes.

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