Authors :
Dr. Tarika Sharma; Dr. Deepak Sharma; Dr. Shanta Negi; Dr. Vinay Kumar Bhardwaj; Dr. Bhawna Singh
Volume/Issue :
Volume 9 - 2024, Issue 6 - June
Google Scholar :
https://tinyurl.com/2a53y233
Scribd :
https://tinyurl.com/3s5dcf3a
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24JUN225
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Background:
Calcium channel blockers (CCBs) are frequently
prescribed for treating cardiovascular conditions.
Amlodipine, a third-generation CCB, is known to cause
gingival enlargement in some patients. This case report
discusses the diagnosis and management of gingival
enlargement induced by amlodipine in a patient with
hypertension.
Methods:
Phase-1 non-surgical periodontal therapy combined
with diode laser gingivectomy and gingivoplasty was
performed for conservative management of the
enlargement.
Results:
Favorable clinical outcome was observed with
excellent gingival healing and more aesthetic gingival
morphology.
Conclusion:
Treatment of drug induced gingival enlargement
with diode laser proved to be moreeffective and resulted
in faster healing and mild discomfort.
References :
- Brown RS, Arany PR. Mechanism of drug‐induced gingival overgrowth revisited: a unifying hypothesis. Oral diseases. 2015 Jan;21(1):e51-61.
- Liu Y, Peng Q, Liu B, Wang Z, Cao Q. Er, Cr: YSGG Laser Therapy for Drug-Induced Gingival Overgrowth: A Report of Two Case Series. Frontiers in Surgery. 2022;9.
- Seymour RA, Thomason JM, Ellis JS. The pathogenesis of drug‐induced gingival overgrowth. Journal of clinical periodontology. 1996 Mar;23(3):165-75.
- Livada R, Shiloah J. Calcium channel blocker-induced gingival enlargement. Journal of human hypertension. 2014 Jan;28(1):10-4.
- Mavrogiannis M, Ellis JS, Thomason JM, Seymour RA. The management of drug‐induced gingival overgrowth. Journal of clinical periodontology. 2006 Jun;33(6):434-9.
- Madi M, Shetty SR, Babu SG, Achalli S. Amlodipine-induced gingival hyperplasia–a case report and review. The West Indian Medical Journal. 2015 Jun;64(3):279.
- Saleem M, Deepa D. Management of amlodipine-induced gingival enlargement by diode laser. Journal of Current Research in Scientific Medicine. 2016 Jan 1;2(1):49.
- Seymour RA, Ellis JS, Thomason JM, Monkman S, Idle JR. Amlodipine‐induced gingival overgrowth. Journal of clinical periodontology. 1994 Apr;21(4):281-3.
- Jorgensen MG. Prevalence of amlodipine‐related gingival hyperplasia. Journal of periodontology. 1997 Jul;68(7):676-8.
- Lafzi A, Farahani RM, Shoja MA. Amlodipine-induced gingival hyperplasia. Medicina Oral, Patología Oral y Cirugía Bucal (Internet). 2006 Dec;11(6):480-2.
- De Oliveira Guaré R, Costa SC, Baeder F, De Souza Merli LA, Dos Santos MT. Drug‐
- induced gingival enlargement: Biofilm control and surgical therapy with galliu aluminum–arsenide (GaAlAs) diode laser—A 2‐year follow‐up. Special Care in Dentistry. 2010 Mar;30(2):46-5.
Background:
Calcium channel blockers (CCBs) are frequently
prescribed for treating cardiovascular conditions.
Amlodipine, a third-generation CCB, is known to cause
gingival enlargement in some patients. This case report
discusses the diagnosis and management of gingival
enlargement induced by amlodipine in a patient with
hypertension.
Methods:
Phase-1 non-surgical periodontal therapy combined
with diode laser gingivectomy and gingivoplasty was
performed for conservative management of the
enlargement.
Results:
Favorable clinical outcome was observed with
excellent gingival healing and more aesthetic gingival
morphology.
Conclusion:
Treatment of drug induced gingival enlargement
with diode laser proved to be moreeffective and resulted
in faster healing and mild discomfort.