Authors :
Manju KC, Dr. Mohammad Mustafa, Dr. Gautam Prasad Chaudhary, Bikram Shrestha, Purushottam Yadav
Volume/Issue :
Volume 5 - 2020, Issue 4 - April
Google Scholar :
https://goo.gl/DF9R4u
Scribd :
https://bit.ly/2KK2OPr
Abstract :
- Mental disorders are the group of disease of
brain which includes anxiety disorder, bipolar disorder,
depression, schizophrenia, insomnia, eating disorder
etc. The main objective of our study is to know about
the prescription pattern of psychotropic drug in
psychiatric out-patient department based on the WHO
drug prescribing indicators. The study design was
observational cross-sectional study; Total 192 patients
were included with mental disorder. The result of this
study shows that most of the patients were from age
group 20-39. Female patients were more than male and
most of the patients were come from rural region.
Brahman patients were mostly found and most of the
patients’ occupation was housewife. Married patients
were more and most of the patients were illiterate. Most
of the patients were Hindu and many patients have
nuclear family structure. Out of 545 drugs psychotropic
drugs were 305. Average number of drugs and
psychotropic drugs prescribed were 2.84 and 1.59
respectively. Only 1.84% drugs were prescribed by
generic name and 29.54% drugs were prescribed from
essential medicine list of Nepal. The most commonly
prescribed drug was clonazepam followed by
escitalopram. In anxiety disorder clonazepam, in
depression escitalopram and in schizophrenia
olanzapine were most commonly prescribed. On
increasing the number of drugs, increasing the
percentage of drug-drug interaction and increasing the
age of the patient, polytherapy was decreasing.
Polytherapy of psychotropic drugs were more and we
found that 9.83% drug-drug interactions were severe. It
is concluded that, psychotropic drugs was mostly
prescribed in which clonazepam drug show highest
percentage of prescription. The prescribing pattern can
be improved by prescribing from essential medicine list
and generic drugs and by reducing drugs per
prescription.
Keywords :
Essential medicine list, Mental disorders, Psychotropic drugs, Polytherapy, World Health Organization.
- Mental disorders are the group of disease of
brain which includes anxiety disorder, bipolar disorder,
depression, schizophrenia, insomnia, eating disorder
etc. The main objective of our study is to know about
the prescription pattern of psychotropic drug in
psychiatric out-patient department based on the WHO
drug prescribing indicators. The study design was
observational cross-sectional study; Total 192 patients
were included with mental disorder. The result of this
study shows that most of the patients were from age
group 20-39. Female patients were more than male and
most of the patients were come from rural region.
Brahman patients were mostly found and most of the
patients’ occupation was housewife. Married patients
were more and most of the patients were illiterate. Most
of the patients were Hindu and many patients have
nuclear family structure. Out of 545 drugs psychotropic
drugs were 305. Average number of drugs and
psychotropic drugs prescribed were 2.84 and 1.59
respectively. Only 1.84% drugs were prescribed by
generic name and 29.54% drugs were prescribed from
essential medicine list of Nepal. The most commonly
prescribed drug was clonazepam followed by
escitalopram. In anxiety disorder clonazepam, in
depression escitalopram and in schizophrenia
olanzapine were most commonly prescribed. On
increasing the number of drugs, increasing the
percentage of drug-drug interaction and increasing the
age of the patient, polytherapy was decreasing.
Polytherapy of psychotropic drugs were more and we
found that 9.83% drug-drug interactions were severe. It
is concluded that, psychotropic drugs was mostly
prescribed in which clonazepam drug show highest
percentage of prescription. The prescribing pattern can
be improved by prescribing from essential medicine list
and generic drugs and by reducing drugs per
prescription.
Keywords :
Essential medicine list, Mental disorders, Psychotropic drugs, Polytherapy, World Health Organization.
