 Aim: Muslims all over the world fast during the Holy month of Ramadan and abstain themselves from taking any kind of food or water during day time. People diagnosed with any kind of illness may abstain from fasting but people continue to fast against medical advice. It is therefore of interest to compare pre and post Ramadan effects on physiological parameters in individuals with metabolic syndrome.  Methodology: A prospective cohort study was conducted on 28 people diagnosed with metabolic syndrome and diabetes mellitus who were ready to fast for the whole month of Ramadan. The main components of metabolic syndrome assessed for the study were: blood sugar, systolic blood pressure, diastolic blood pressure and body mass index (BMI).  Result: The mean age of the study population was 46.46±3.61 years, with females (86%) and males (14%). The mean HbA1c was 8±1.169%, and the mean height of the study population was 158.07±7.54 cm. Weight reduced from pre-Ramadan to during Ramadan and post Ramadan assessment periods were highly statistically significant (p=.000). BMI showed a reduction in the 3 assessment periods and the difference seen was highly statistically significant (p=.000). The comparison of blood sugar at 3 time periods showed that the blood sugar reduced in the study population from pre-Ramadan, during Ramadan and post Ramadan assessment periods and the difference seen was not statistically significant (.385). Systolic blood pressure seemed to be reduced in the study population from pre-Ramadan, during and post Ramadan assessment periods and the difference showed a borderline significance (.072). Diastolic blood pressure seemed to be reduced in the study population from pre- Ramadan to during and post Ramadan assessment periods and the difference was statistically significant (.002).  Conclusion: Ramadan fasting have positive effects on parameters of metabolic syndrome like weight, BMI, and blood pressure.

Keywords : Ramadan, Fasting, Metabolic Syndrome.