Authors : Nia Afdilla; Suhikma Sofyan; Reymon; Musdalipah; Bonni Rubak

Volume/Issue : Volume 10 - 2025, Issue 1 - January

Google Scholar : https://tinyurl.com/yh4u7pj9

Scribd : https://tinyurl.com/mtzzd45a

DOI : https://doi.org/10.5281/zenodo.14737922

Abstract : Zingiberaceae has high biological activity in treating various diseases. One of the largest genera of Zingiberaceae is Alpinia, found in tropical and subtropical regions—some of the newly discovered generations of Zingiberaceae such as the genus Alpinia and Meistera. The Alpinia genus found in Southeast Sulawesi is the Wundu Watu plant (Alpinia monopleura). Alpinia monopleura contains secondary metabolites such as lignin, flavonoids, and diterpenoids that have antibacterial activity. The purpose of this study was to prepare a herbal toothpaste formulation of wundu watu extract with a concentration of 30%. The research design used is the maceration method using 96% ethanol solvent, this research design uses experimental methods in the laboratory. The preparation formulation was evaluated by organoleptic test, homogeneity test, physical stability test, liking test, pH test, viscosity test, foam formation, bacterial activity, and a decrease in the plaque index causing dental caries. The results showed a statistical test of Paired Sample T-Test significant p (<0.05) toothpaste containing Wundu Watu extract (Alpinia Monopleura) has effectiveness against bacteria that cause plaque and dental caries at a concentration of 30%. The toothpaste formulation of Wundu Watu extract provides servant power against Streptococcus mutans.

Keywords : Wundu Watu; Zingiberaceae; Streptococcus Mutans; Dental Caries; Plaque.

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