Authors :
Ringkangmai Liangkiuwiliu; Dr. Sonal Chand; Dr. Mohnyca Yumnam; Dr. Imran Khan
Volume/Issue :
Volume 10 - 2025, Issue 6 - June
Google Scholar :
https://tinyurl.com/5d6svjs8
DOI :
https://doi.org/10.38124/ijisrt/25jun1227
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Introduction: Uterine fibroids, frequently referred to as leiomyomas or myomas, are the most widespread kind of
benign uterine tumour. They can range in size, shape, and position within the uterus from unnoticeable nodules to huge
masses that can deform the uterus. They are made up of cells of smooth muscles and fibrous connective tissue. Clinical
manifestations include obstetric issues, infertility, bulk symptoms, abnormal bleeding, pelvic lumps, and pelvic discomfort.
Over one third of women with leiomyomas will seek therapy as a result of their symptoms. It has a significant impact on
50% of women who are of reproductive age and 80% of women by beyond the age of 50. Aim: The aim of this study is to
find out the effectiveness of Turmeric Green Tea on Physiological parameters and quality of life among women with uterine
fibroids. Methodology: Intervention- Turmeric Green Tea. Here is a paraphrased version of your statement. Study Design:
A randomized controlled trial utilizing a pre-test and post-test design with a placebo control group. Participants: Women
diagnosed with uterine fibroids experiencing mild to moderate symptoms. Setting: Liangmai Community, Manipur.
Outcome: This review result will show that Turmeric Green will be effective on physiological parameters and quality of life
among women uterine fibroids.
Keywords :
Uterine Fibroid/Leiomyomas/Uterine Tumour, Physiological Parameters, Quality of Life.
References :
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- Adham B., et al., (2022).The use of green tea in the treatment of symptomatic uterine fibroid. International Journal of Health Sciences, 6(S1), 3116–3135. https://doi.org/10.53730/ijhs.v6nS1.5353
- V. R. Sinija and H. N. Mishra.(2008). Green tea: health benefits. Journal of Nutritional & Environmental Medicine December 2008; 17(4): 232–242. EBSCO
- Ahmed, R. et al. (2016). Biological and Mechanistic Characterization of Novel Prodrugs of Green Tea Polyphenol Epigallocatechin Gallate Analogs in Human Leiomyoma Cell Lines. J. Cell. Biochem. 2016, 117, 2357–2369. [CrossRef] [PubMed]
- Hendy A., et al., (2023). Fibroids and unexplained infertility treatment with epigallocatechin gallate: a natural compound in green tea (FRIEND) – protocol for a randomised placebo-controlled US multicentre clinical trial of EGCG to improve fertility in women with uterine fibroids. BMJ Open 14(1):e078989: DOI:10.1136/bmjopen-2023-078989
- Zhang, D. et al. (2010). Green tea extract inhibits proliferation of uterine leiomyoma cells in vitro and in nude mice. Am. J. Obstet. Gynecol. 2010, 202, 289.e1–289.e9. [CrossRef] [PubMed]
- Siblini. H., et.al., (2023). Assessing the Hepatic Safety of Epigallocatechin Gallate (EGCG) in Reproductive-Aged Women. Nutrients 2023, 15, 320. https://doi.org/10.3390/nu15020320
- Rebekka B. et al. (2022). Effects of epigallocatechin gallate-enriched green tea extract capsules in uterine myomas: results of an observational study. Arch Gynecol Obstet. 2021 May;303(5):1235-1243. doi: 10.1007/s00404-020-05907-6. Epub 2021 Jan 2.
- Roshdy, E. et al. (2013). A. Treatment of symptomatic uterine fibroids with green tea extract: A pilot randomized controlled clinical study. International Journal Women’s Health 2013, 5, 477–486.
- Hewlings S.J., Kalman D.S. Curcumin: A Review of Its Effects on Human Health. Foods. 2017; 692. 10.3390/foods6100092. 29065496
- Bai, et al.,(2023).The combination of natural compounds Crila and epigallocatechin gallate showed enhanced antiproliferative effects on human uterine fibroid cells compared with single treatments. Fertil Steril Sci® Vol. 4, No. 4, November 2023 2666-335X (http://creativecommons.org/licenses/by/4.0/).https://doi.org/10.1016/j.xfss.2023.09.004
- Siblini H. et al., (2021) EGCG for the treatment of unexplained infertility associated with UF: early safety assessment. Fertility and Sterility. 116(3), 2021.
- Kenji T., et al., (2010). Inhibitory effect of curcumin on uterine leiomyoma cell proliferation. Gynaecological endocrinology. 27(7); https://doi.org/10.3109/09513590.2010.507287
- Malik M., et al., (2009). Curcumin, a nutritional supplement with antineoplastic activity, enhances leiomyoma cell apoptosis and decreases fibronectin expression. Fertility and Sterility. 91(5), 2009: doi:10.1016/j.fertnstert.2008.03.045
- Malik M., et al., (2023). Curcumin inhibits human leiomyoma xenograft tumor growth and induces dissolution of the extracellular matrix. Fertility and Sterility. 4(1); https://doi.org/10.1016/j.xfss.2022.10.004
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Introduction: Uterine fibroids, frequently referred to as leiomyomas or myomas, are the most widespread kind of
benign uterine tumour. They can range in size, shape, and position within the uterus from unnoticeable nodules to huge
masses that can deform the uterus. They are made up of cells of smooth muscles and fibrous connective tissue. Clinical
manifestations include obstetric issues, infertility, bulk symptoms, abnormal bleeding, pelvic lumps, and pelvic discomfort.
Over one third of women with leiomyomas will seek therapy as a result of their symptoms. It has a significant impact on
50% of women who are of reproductive age and 80% of women by beyond the age of 50. Aim: The aim of this study is to
find out the effectiveness of Turmeric Green Tea on Physiological parameters and quality of life among women with uterine
fibroids. Methodology: Intervention- Turmeric Green Tea. Here is a paraphrased version of your statement. Study Design:
A randomized controlled trial utilizing a pre-test and post-test design with a placebo control group. Participants: Women
diagnosed with uterine fibroids experiencing mild to moderate symptoms. Setting: Liangmai Community, Manipur.
Outcome: This review result will show that Turmeric Green will be effective on physiological parameters and quality of life
among women uterine fibroids.
Keywords :
Uterine Fibroid/Leiomyomas/Uterine Tumour, Physiological Parameters, Quality of Life.