Authors :
Gbenga Damilola Akinlua; Idowu Pius Ade-Ojo; Jacob Olumuyiwa Awoleke; Tolulope Benedict Adeyanju; Toyin Julius Oluleye; Ekundayo Oluwole Ayegbusi; Samson Gbenga Oluwayomi; Omoyemi Adeoti Akinlua; Margaret Adefiola Oluwayemi; Kehinde Peter Animasahun
Volume/Issue :
Volume 9 - 2024, Issue 3 - March
Google Scholar :
https://tinyurl.com/bdfe27vm
Scribd :
https://tinyurl.com/26vupmd8
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24MAR1842
Abstract :
This study aims to compare the effectiveness of
prophylactic intravenous Tranexamic acid (TXA) dosages
of 0.5g and 1.0g in the prevention of postpartum
haemorrhage (PPH) among parturient with risk factors.
The research followed a randomized, double-blind,
controlled experimental design, spanning nine months.
Simple random sampling was used to select 154
participants to each arm. The research objectives
encompassed comparing labour outcomes of the two
groups and measuring blood loss via pre and post-delivery
packed cell volume. Statistical analysis employed Student's
t-test. Result revealed a slight non-significant difference in
PCV change between 0.5g and 1.0g TXA group. The study
also found that the risk of developing primary PPH when
using 0.5g TXA was approximately twice the risk when
using 1.0g TXA. These findings suggest that the
prophylactic use of 1.0g TXA may be more effective in
preventing PPH compared to 0.5g TXA. Further research
is warranted to validate these results and refine
recommendations for clinical practice.
Keywords :
Tranexamic Acid, Blood Loss, High-Risk Factors, Third Stage Of Labour, Parturient.
This study aims to compare the effectiveness of
prophylactic intravenous Tranexamic acid (TXA) dosages
of 0.5g and 1.0g in the prevention of postpartum
haemorrhage (PPH) among parturient with risk factors.
The research followed a randomized, double-blind,
controlled experimental design, spanning nine months.
Simple random sampling was used to select 154
participants to each arm. The research objectives
encompassed comparing labour outcomes of the two
groups and measuring blood loss via pre and post-delivery
packed cell volume. Statistical analysis employed Student's
t-test. Result revealed a slight non-significant difference in
PCV change between 0.5g and 1.0g TXA group. The study
also found that the risk of developing primary PPH when
using 0.5g TXA was approximately twice the risk when
using 1.0g TXA. These findings suggest that the
prophylactic use of 1.0g TXA may be more effective in
preventing PPH compared to 0.5g TXA. Further research
is warranted to validate these results and refine
recommendations for clinical practice.
Keywords :
Tranexamic Acid, Blood Loss, High-Risk Factors, Third Stage Of Labour, Parturient.
