Authors : Ismael Coulibaly; Saleh Abdelkerim Nedjim; Abou DAO; Chékrine Tarik; Mouna Bourhafour; Zineb Bouchbika; Nadia Benchakroun; Mohammad Dakir; Hassan Jouhadi; Nezha Tawfiq; Souha Sahraoui

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

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DOI : https://doi.org/10.5281/zenodo.7828343

Abstract :  Background Kidney cancer in adults has a high metastatic potential with poor survival rates. Pronostic factors would improve the choice of a therapeutic method. We decided to revisit epidemiology and evaluate survival factors in kidney metastatic carcinomas in a Moroccan setting.  Method: Retrospective data collect from 2017 to 2020 of all adults patients presenting with metastatic kidney carcinomas. Epidemiology and survival rates were analysed using SPSS.  Results: We included 79 patients, predominantly over 60yo and male. Metastases were observed in lungs (73.4%), lymph nodes (39.2%), livers (31.6%), bones (35.4%) and peritoneum (17.8%). Metastases were concurrent to the primitive tumor in 59.5%. Histology was predominantly clear cell renal carcinoma. According to IMDC score, 77% of patients had an intermediate score. Global survival was 29%, better for patients with an intermediate score (p=0.009) as well as progression free survival (p=0.001). In multivariate analysis, only the OMS performance status (p=0.008) and height (0.02) were associated with survival.  Conclusion Thé IMDC score is a suitable tool to classify patients with metastatic kidney cancers, in order to guide therapeutic choices.

Keywords : Epidemiology, Kidney, Cancer, Metastatic, Survival, Morocco.