Evaluating Curcumin and Bromelain as Dentin Biomodifiers for Enhancing Shear Bond Strength – An Invitro study


Authors : Dr. Aju Anto Puthur; Dr. Moksha Nayak; Dr. Rohini B; Dr. Gagan Gopal G.

Volume/Issue : Volume 9 - 2024, Issue 9 - September


Google Scholar : https://tinyurl.com/4sabc8ea

Scribd : https://tinyurl.com/ypvmdr2p

DOI : https://doi.org/10.38124/ijisrt/IJISRT24SEP1198

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Aim To evaluate the effect of collagen stabilizing agents like Curcumin and Bromelain enzyme on the shear bond strength of restorative resin to dentin.  Materials and Methods Thirty single rooted, non carious human mandibular premolars were selected and decoronation was done. The tooth was then mounted. Etchant was applied to the dentin samples and divided into 3 experimental groups. Group 1 (Control - Bonding agent + Composite); Group 2 (Pre-treatment with Curcumin for 30 sec + Rinsing + Bonding agent + Composite). Group 3(Pre-treatment with Bromelain enzyme for 30 sec + Rinsing + Bonding agent + Composite). Following this, total etch adhesive was applied and light. Nanohybrid composite restoration was done. Then the samples were subjected to shear bond strength. The load was applied to the bonded interface with a cross-head speed of 0.5 mm / minute until fracture occurred.  Results The mean values Shear bond strength of dentin were slightly more in bromelain enzyme (48.49), seconded by curcumin (38.80), followed by control group (27.23). The difference was statistically significant among the three different remineralising agent used.  Conclusion Bromelain enzyme showed the highest mean shear bond strength value when compared to the other experimental group.

Keywords : Decoronation, Etching, Shear Bond Strength.

References :

  1. Varghese AS, prakash V, mitthra S, mary NS, deepti JV, subbiya A, nilofer J. Role of different collagen cross-linking agents like proanthocyanidin, riboflavin and white tea on the shear bond strength to dentin-an in-vitro study. NVEO-NATURAL VOLATILES & ESSENTIAL OILS journal| NVEO. 2021 nov 22:6396-407.
  2. Nagpal r, agarwal m, mehmood n, singh up. Dentin biomodifiers to stabilize the bonded interface. Mod res dent. 2020 mar 6; 5:543-8.
  3. Liu y, wang y. Proanthocyanidins’ efficacy in stabilizing dentin collagen against enzymatic degradation: MALDI-TOF and FTIR analyses. J dent 2013; 41: 535-42
  4. Zhou w, liu s, zhou x, hannig m, rupf s, et al. (2019) modifying adhesive materials to improve the longevity of resinous restorations. Int J mol sci 20(3): 723.
  5. Dayem RN, Tameesh MA. A new concept in hybridization: Bromelain enzyme for deproteinizing dentin before application of adhesive system. Contemporary clinical dentistry. 2013 Oct 1;4(4):421-6.

Aim To evaluate the effect of collagen stabilizing agents like Curcumin and Bromelain enzyme on the shear bond strength of restorative resin to dentin.  Materials and Methods Thirty single rooted, non carious human mandibular premolars were selected and decoronation was done. The tooth was then mounted. Etchant was applied to the dentin samples and divided into 3 experimental groups. Group 1 (Control - Bonding agent + Composite); Group 2 (Pre-treatment with Curcumin for 30 sec + Rinsing + Bonding agent + Composite). Group 3(Pre-treatment with Bromelain enzyme for 30 sec + Rinsing + Bonding agent + Composite). Following this, total etch adhesive was applied and light. Nanohybrid composite restoration was done. Then the samples were subjected to shear bond strength. The load was applied to the bonded interface with a cross-head speed of 0.5 mm / minute until fracture occurred.  Results The mean values Shear bond strength of dentin were slightly more in bromelain enzyme (48.49), seconded by curcumin (38.80), followed by control group (27.23). The difference was statistically significant among the three different remineralising agent used.  Conclusion Bromelain enzyme showed the highest mean shear bond strength value when compared to the other experimental group.

Keywords : Decoronation, Etching, Shear Bond Strength.

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