Evaluation of Phytochemical and Antimicrobial Activity of Achyranthus aspera


Authors : Tripathi Keerti; Rai. O. P; Nigam.R.S.

Volume/Issue : Volume 8 - 2023, Issue 12 - December

Google Scholar : http://tinyurl.com/2v97jtya

Scribd : http://tinyurl.com/56pckd85

DOI : https://doi.org/10.5281/zenodo.10390526

Abstract : Bioactive chemicals found in medicinal plants are used to treat a variety of illnesses. The medicinal herb Achyranthus aspera is the subject of the current inquiry. The aim of the current investigation was screening of phytochemicals and antibiotic activity of whole plant methanol extract against a few pathogenic fungi and bacteria. seven distinct solvents such as water, acetone, methanol, ethanol, diethyl ether, benzene, and chloroform were used for phytochemical screening of the plant's root, stem, and leaf. Using a conventional technique, the extracts were subjected to qualitative phytochemical screening. Alkaloids, Saponins, Tannins, Steroids, Glycosides, and Flavonoids are all detected by phytochemical screening. Achyranthus aspera demonstrated antimicrobial properties against microorganism. According to this investigation, the methanolic extract had the strongest antibacterial efficacy against practically all test microorganisms. The extract exhibited a maximum of 15 mm zone of inhibition when tested against Total Coliform, and a minimum of 8 mm zone of inhibition when tested against Salmonela aureginosa.

Keywords : Achyranthes aspera, Root, Stem and Leaf Phytochemical Screening, Antibacterial, Secondary Metabolites, Bioactive.

Bioactive chemicals found in medicinal plants are used to treat a variety of illnesses. The medicinal herb Achyranthus aspera is the subject of the current inquiry. The aim of the current investigation was screening of phytochemicals and antibiotic activity of whole plant methanol extract against a few pathogenic fungi and bacteria. seven distinct solvents such as water, acetone, methanol, ethanol, diethyl ether, benzene, and chloroform were used for phytochemical screening of the plant's root, stem, and leaf. Using a conventional technique, the extracts were subjected to qualitative phytochemical screening. Alkaloids, Saponins, Tannins, Steroids, Glycosides, and Flavonoids are all detected by phytochemical screening. Achyranthus aspera demonstrated antimicrobial properties against microorganism. According to this investigation, the methanolic extract had the strongest antibacterial efficacy against practically all test microorganisms. The extract exhibited a maximum of 15 mm zone of inhibition when tested against Total Coliform, and a minimum of 8 mm zone of inhibition when tested against Salmonela aureginosa.

Keywords : Achyranthes aspera, Root, Stem and Leaf Phytochemical Screening, Antibacterial, Secondary Metabolites, Bioactive.

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