Authors :
Dr. Jinu Elizabeth James; Dr. K Shashidhara Kamath; Dr. K. S. Manjunath; Dr. Adarsh L. Pawar; Dr. Vijay Kumar Jain
Volume/Issue :
Volume 8 - 2023, Issue 5 - May
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/32tjv435
DOI :
https://doi.org/10.5281/zenodo.8049647
Abstract :
Background and Objectives: Lignocaine Hydrochloride
(HCl), an amide group of local anaesthetic continues to
be used as the preferred local anaesthetic agent in
exodontia. Alternatives such as diphenhydramine, an
antihistamine is used in cases of allergy exhibited
towards amide or ester group of local anaesthetic agents.
Other alternatives such as opioids like tramadol
hydrochloride (HCl) have recently shown peripheral
anaesthetic activity. The present double-blinded splitmouth clinical study aimed to evaluate and compare the
clinical anaesthetic efficacy, analgesic effect, and
limitations of lignocaine HCl and tramadol HCl in
orthodontic extractions.
Methods: 100 cases were selected for the orthodontic
extraction of maxillary premolars. 50 healthy and
ambulatory individuals of both sexes, aged 18- 30 years
undergoing extraction of bilateral maxillary premolar
teeth for orthodontic treatment, fulfilling the inclusion
criteria were selected for the study.
Keywords :
Tramadol HCl, Lignocaine HCl, local anaesthesia, analgesic effect.
Background and Objectives: Lignocaine Hydrochloride
(HCl), an amide group of local anaesthetic continues to
be used as the preferred local anaesthetic agent in
exodontia. Alternatives such as diphenhydramine, an
antihistamine is used in cases of allergy exhibited
towards amide or ester group of local anaesthetic agents.
Other alternatives such as opioids like tramadol
hydrochloride (HCl) have recently shown peripheral
anaesthetic activity. The present double-blinded splitmouth clinical study aimed to evaluate and compare the
clinical anaesthetic efficacy, analgesic effect, and
limitations of lignocaine HCl and tramadol HCl in
orthodontic extractions.
Methods: 100 cases were selected for the orthodontic
extraction of maxillary premolars. 50 healthy and
ambulatory individuals of both sexes, aged 18- 30 years
undergoing extraction of bilateral maxillary premolar
teeth for orthodontic treatment, fulfilling the inclusion
criteria were selected for the study.
Keywords :
Tramadol HCl, Lignocaine HCl, local anaesthesia, analgesic effect.