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Explainable Deep Neural Networks for Neurological Disorder Classification: A Focus on Parkinson’s Disease Tremor Analysis Via Wearable Sensor Fusion


Authors : Utsha Sarker; Aman Singh; Archy Biswas; Santosh Rai; Vikash Prajapati

Volume/Issue : Volume 11 - 2026, Issue 3 - March


Google Scholar : https://tinyurl.com/4uy33uxy

Scribd : https://tinyurl.com/3chts2bz

DOI : https://doi.org/10.38124/ijisrt/26mar007

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Parkinson's disease (PD) is a progressive degenerating disease with motor manifestations that include resting tremor, bradykinesia and rigidity. Accurate assessment of tremor is still very much reliant on subjective clinical scale criteria (Unified Parkinson's Disease Rating Scale (UPDRS)) that may not represent minor fluctuations or real world variability. This restriction highlights an obvious lack of objective, ongoing and comprehended tremor monitoring solutions to help with early diagnosis and personalized disease management. In this study, an explainable deep learning framework used for tremor classification based on wearable sensor fusion is proposed. Wrist worn accelerometer signals and gyroscope signals are fused and processed using the hybrid system of 1-D Convolution Neural Networks (1-D CNN) merged with the Bidirectional Long Short-Term Memory (BiLSTM) which can capture both the local motion patterns and long-term temporal dependencies. More transparency is provided by explainable AI methods (Grad-CAM and SHAP) to explain important segments of the time, as well as the role of the sensor in the prediction of the model. Experiments were performed on a data set containing 62 subjects (38 PD patients and 24 healthy subject), which was recorded at 100 Hz. Signals were divided in 1.28 sec overlapped t ime windows, and were labeled as tremor or not tremor, PD or control. The proposed model showed 94.3%, 93.8%, 0.96 AUC, 92.5%, 95.1% accuracy, F1-score, sensitivity, and specificity, respectively, which are much better than conventional CNN and SVM approximations with accuracy improvements of 6-9%. Explainability analysis showed an overriding influence of tremor-related oscillatory components (4-6 Hz) in the prediction, which led to clinically meaningful explainability of the predictions, and gives extra confidence to the model for use in the real world.

Keywords : Parkinson's Disease, Wearable Sensors, Deep Neural Network, Tremor Detection, Explainable Artificial Intelligence (XAI), Sensor Fusion.

References :

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  2. Y. X. Teo, R. E. Lee, S. G. Nurzaman, C. P. Tan, and P. Y. Chan, “Action tremor features discovery for essential tremor and Parkinson’s disease with explainable multilayer BiLSTM,” Comput. Biol. Med., vol. 180, Art. no. 108957, Sep. 2024, doi: 10.1016/j.compbiomed.2024.108957.
  3. T. Sil et al., “Sensor-based data-driven differentiation between Parkinson’s tremor and essential tremor,” Expert Syst. Appl., vol. 299, pt. D, Art. no. 130336, Mar. 2026, doi: 10.1016/j.eswa.2025.130336.
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  12. J. Varghese et al., “Machine Learning in the Parkinson’s disease smartwatch (PADS) dataset,” npj Parkinson’s Dis., vol. 10, Art. no. 9, 2024, doi: 10.1038/s41531-023-00625-7.
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  14. H. Mughal, A. R. Javed, M. Rizwan, A. S. Almadhor, and N. Kryvinska, “Parkinson’s disease management via wearable sensors: a systematic review,” IEEE Access, vol. 10, pp. 35219–35237, 2022, doi: 10.1109/ACCESS.2022.3162844.
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Parkinson's disease (PD) is a progressive degenerating disease with motor manifestations that include resting tremor, bradykinesia and rigidity. Accurate assessment of tremor is still very much reliant on subjective clinical scale criteria (Unified Parkinson's Disease Rating Scale (UPDRS)) that may not represent minor fluctuations or real world variability. This restriction highlights an obvious lack of objective, ongoing and comprehended tremor monitoring solutions to help with early diagnosis and personalized disease management. In this study, an explainable deep learning framework used for tremor classification based on wearable sensor fusion is proposed. Wrist worn accelerometer signals and gyroscope signals are fused and processed using the hybrid system of 1-D Convolution Neural Networks (1-D CNN) merged with the Bidirectional Long Short-Term Memory (BiLSTM) which can capture both the local motion patterns and long-term temporal dependencies. More transparency is provided by explainable AI methods (Grad-CAM and SHAP) to explain important segments of the time, as well as the role of the sensor in the prediction of the model. Experiments were performed on a data set containing 62 subjects (38 PD patients and 24 healthy subject), which was recorded at 100 Hz. Signals were divided in 1.28 sec overlapped t ime windows, and were labeled as tremor or not tremor, PD or control. The proposed model showed 94.3%, 93.8%, 0.96 AUC, 92.5%, 95.1% accuracy, F1-score, sensitivity, and specificity, respectively, which are much better than conventional CNN and SVM approximations with accuracy improvements of 6-9%. Explainability analysis showed an overriding influence of tremor-related oscillatory components (4-6 Hz) in the prediction, which led to clinically meaningful explainability of the predictions, and gives extra confidence to the model for use in the real world.

Keywords : Parkinson's Disease, Wearable Sensors, Deep Neural Network, Tremor Detection, Explainable Artificial Intelligence (XAI), Sensor Fusion.

Paper Submission Last Date
31 - March - 2026

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