Authors : Devendra Patil; Jagruti Badgujar; Bhavesh Mistari; Ruchira Gajbhiye; Manoj Girase; Umesh Koli

Volume/Issue : Volume 10 - 2025, Issue 4 - April

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DOI : https://doi.org/10.38124/ijisrt/25apr1174

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Abstract : Prunus cerasoides, also known as PADMAKA, is a tree found in the Himalayan region. It has been used in ayurveda because it contains natural compounds that help to resolve the skin problems. This study aims to formulate and evaluate a face serum using PADMAKA, combining traditional herbal knowledge with modern cosmetic science. In this study we formulate the face serum using appropriate ingredients and also characterized the pH, thickness and spreadability of formulation. Safety parameters such as skin irritation and germ contamination tests are performed. The serum's effects on skin hydration, brightening, and anti-aging was also studied on lab scale and real-life use. Finally, people's opinions will be collected to see if the serum is effective and can be sold in the market. The obtained results conclude that the formulated PADMAKA-based serum is safe, stable, and useful for natural skincare.

Keywords : Serum, Skin lightening, Prunus Cerasoides, Skincare.

References :

1. Sharma, I,Tyagi, M., & Sharma, R. (2022).A Review on PADMAK(pruns cerasoides) An emerging Traditional Drug for Therapeutic Benefits. Vol 11, Issue 9, 2022. │ ISO 9001:2015 Certified Journal  637-638.
2. Joseph, N, Anjum, N., & Tripathi, Y. C. (2018). Prunus cerasoides D. Don: a review on its ethnomedicinal uses, phytochemistry and pharmacology.Int. J. Pharm. Sci. Rev. Res., 48(1), January - February 2018; Article No. 15, 62-69
3. http://www.globalresearchonline.net/
4. Bade, S. S, & Deo, S. Pharmacological Action of Padmak Agada in Skin Ailments. Volume 6, Issue 3, May-June 2024; 1-2.
5. https://www.ijfmr.com/
6. Jyotshna, & Shanker, K. An Insight Review on Phytochemistry, Pharmacological Evidences, and Biosynthesis of Key Metabolites of Indian Himalayan Cherry (Prunus cerasoides Don.) with Emphasis on its Safety and Use in Traditional Phytomedicine. Chemistry & Biodiversity, e202401814. https://doi.org/10.1002/cbdv.202401814
7. Sundar, B, & Gadad, G. G. Scope of Varnya Mahakashaya Drugs as A Key Component to Health From A Cosmetic Perspective. Vol. 5 (3),142-150, March, 2022 https://doi.org/10.47223/IRJAY.2022.5321
8. Rizzi, V, Gubitosa, J, Fini, P, & Cosma, P. (2021). Neurocosmetics in skincare the fascinating world of skin–brain connection: a review to explore ingredients, commercial products for skin aging, and cosmetic regulation. Cosmetics, 8(3), 66. https://doi.org/10.3390/cosmetics8030066
9. Al-Sarraf,A.(2022). Skin lightening as an image enhancing phenomenon: investigating risks, motivations, and underlying psychological factors. https://doi.org/10.18745/th.25837
10. Ekpunobi, U. E, Okonkwo, E. O, Udeh, C. V, Ogbuagu, A. S, & Duru, C. B. (2014). Determination of hydroquinone and mercury concentrations in some skin lightening lotions and creams sold in Southeastern Nigeria.
11. http://repository.unizik.edu.ng/handle/123456789/726
12. Rossi, D., & Realdon, N. (2021). Surface tensiometry approach to characterize cosmetic products in the beauty sector. Surface Science and Adhesion in Cosmetics, 309-352. https://doi.org/10.1002/9781119654926.ch10
13. Khan, N, Ahmed, S, Sheraz, M. A, Anwar, Z., & Ahmad, I. (2023). Pharmaceutical based cosmetic serums. In Profiles of Drug Substances, Excipients and Related Methodology(Vol.48,pp.167-210).AcademicPress. https://doi.org/10.1016/bs.podrm.2022.11.006
14. Patel, P, Pal, R., Butani, K., Singh, S, & Prajapati, B. G. (2023). Nanomedicine-fortified cosmeceutical serums for the mitigation of psoriasis and acne. Nanomedicine, 18(24), 1769-1793. https://doi.org/10.2217/nnm-2023-0147
15. Rizzi, V, Gubitosa, J, Fini, P, & Cosma, P. (2021). Neurocosmetics in skincare the fascinating world of skin–brain connection: a review to explore ingredients, commercial products for skin aging, and cosmetic regulation. Cosmetics, 8(3), 66. https://doi.org/10.3390/cosmetics8030066
16. Pollock, S, Taylor, S, Oyerinde, O, Nurmohamed, S, Dlova, N, Sarkar, R, & Kourosh, A. S. (2021). The dark side of skin lightening: An international collaboration and review of a public health issue affecting dermatology. International journal of women's dermatology, 7(2), 158-164. https://doi.org/10.1016/j.ijwd.2020.09.006
17. Baig, S. A. (2024). Exploring Indian Knowledge System: Veda and Life Science. SGSHPublications. https://books.google.co.in/googlebooks/images/kennedy/insert_link.png
18. Kamble, R,Gamare, D, Yeole, P, Pathan, M. A, Indulkar, A., Kale, M. K., & Juvatkar, P. V. (2022). Formulation and evaluation of herbal based anti-aging face serum. Foldscope & its Applications, 127.
19. Dini, I, & Laneri, S. (2021). The new challenge of green cosmetics: Natural food ingredients for cosmetic formulations. Molecules, 26(13), 3921 https://doi.org/10.3390/molecules26133921
20. Amir M, Zafar A, Ahmad R, Ahmad W, Sarafroz M, Khalid M, Ghoneim MM, Alshehri S, Wahab S, Ahmad S, Mujeeb M. Quality Control Standardization, Contaminant Detection and In Vitro Antioxidant Activity of Prunus domestica LinnFruitPlants(Basel).2022Mar6;11(5):706. https://pubmed.ncbi.nlm.nih.gov/35270176/
21. Di Vaio C, Marallo N, Graziani G, Ritieni A, Di Matteo A. Evaluation of fruit quality, bioactive compounds and total antioxidant activity of flat peach cultivars. J Sci Food Agric. 2015 Aug 15;95(10):2124-31. doi: 10.1002/jsfa.6929. Epub 2014 Oct 28. PMID: 25257768.
22.  https://pubmed.ncbi.nlm.nih.gov/15796596/
23. Okoduwa, S. I. R, Okpe, O, Okoduwa, U. J, Igiri, B. E, Mhya, D. H, & Mbora, L. O. (2018).
24. Comparison of yield and phytoconstituents of Vernonia amygdalina and Ocimum gratissimum leaves extract from three extraction methods. Int J Biomed Clin Sci, 3(2), 27-34.
25. http://www.aiscience.org/journal/ijbc
26. Maheshwaran, L, Nadarajah, L, Senadeera, S. P. N. N, Ranaweera, C. B, Chandana, A.K, & Pathirana, R. N. (2024). Phytochemical Testing Methodologies and Principles for Preliminary Screening/Qualitative Testing. Asian Plant Research Journal, 12(5), 11-38. https://doi.org/10.9734/aprj%2F2024%2Fv12i5267
27. Brazdovlcova B, Kostalova D, Tomko J, Jin HY. Isolation and identification of alkaloids from fruits of Berberisthunbergii DC. Chem zvesti. 1980; 34:259–262.
28. Hasan, M. Z., & Khalil, I. Phytochemical Profiling, Elemental Constituents and Antimicrobial Efficacy of the Sponge Haliclona oculata Collected off the Bay of Bengal.
29.   https://www.isu.ac.bd/research/journal/journal-of-engineering-and-technology
30. Alamgir, A. N. M., & Alamgir, A. N. M. (2018). Methods of Qualitative and Quantitative Analysis of Plant Constituents. Therapeutic Use of Medicinal Plants and their Extracts: Volume 2: Phytochemistry and Bioactive Compounds, 721-804. https://link.springer.com/chapter/10.1007/978-3-319-92387-1_9
31. Rana, N, Kumari, R, & Kumari, P. Phytochemical Screening Photoluminance Study and TLC (Thin Layer Chromatography) of Ficus Religiosa Leaves Extract. https://www.ijpsjournal.com/
32. Wu, J, Beta, T, & Corke, H. (2006). Effects of salt and alkaline reagents on dynamic rheological properties of raw oriental wheat noodles. Cereal Chemistry, 83(2), 211-217.
33. https://doi.org/10.1094/CC-83-0211
34. Oleszek, W. A. (2002). Chromatographic determination of plant saponins. Journal of chromatography A, 967(1), 147-162. https://doi.org/10.1016/S0021-9673(01)01556-4
35. Ranaweera, C. B, Maheshwaran, L, Nadarajah, L, Senadeera, S. P. N. N, Chandana, A. K, & Pathirana, R. N. (2024). Phytochemical Testing Methodologies and Principles for Preliminary Screening/Qualitative Testing.
36.  http://ir.kdu.ac.lk/handle/345/7592
37. Kotnala, A, Velma, K, Sharma, A, Parashar, S, Rathi, B., Kumar, R, & Singh, J. (2019). Indian Medicinal Plants for skin care and cosmeceuticals: A review. Journal of Biomedical and Therapeutic Sciences, 6(2), 24-60 http://pubs.iscience.in/journal/index.php/jbts/article/view/936
38. Evaluation parameter:
39. https://ningen.com/products/vitamin-c-e-face-serum?srsltid=AfmBOorAwed-qTmZGd-YW-S0qXmmOkOo1FbRF6mQ5RYzZ5Rr2veyZ-Z1