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Extensive Intra-Abdominal Hydatidosis Despite Five Years of Intermittent Albendazole Therapy: Surgical Management of a Rare Case


Authors : Dr. J. G. Vagadiya; Dr. Kapil Chakrani; Dr. Disha Padhi; Dr. Devanshu Jaishwal

Volume/Issue : Volume 11 - 2026, Issue 6 - June


Google Scholar : https://tinyurl.com/3pm2m79z

DOI : https://doi.org/10.38124/ijisrt/26jun1662

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Abstract : Cystic Echinococcus is a neglected zoonotic disease caused by the larval stage of Echinococcus granulosus, commonly affecting liver and lungs and may rarely present as disseminated intra-abdominal disease with recurrent lesions despite medical therapy. We report the case of a 40-year-old male who was diagnosed with multiple intra-abdominal hydatid cysts in 2020 involving the liver, spleen, mesentery, peritoneum, and pelvis. The patient was treated with prolonged albendazole therapy and followed up regularly; however, serial imaging demonstrated persistent disease with multiple recurrences and progressive enlargement of cystic lesions. In 2026, imaging revealed a large multiloculated hydatid cyst in the right lobe of the liver with daughter cysts and focal hepatic capsular breach, along with multiple cysts in the spleen and widespread peritoneal, mesenteric, and pelvic involvement causing mass effect on adjacent structures. In view of extensive disease progression and failure to respond to medical management, the patient underwent definitive surgical intervention. This case highlights the challenges in managing disseminated hydatid disease, the potential for recurrence despite prolonged antiparasitic therapy, and the important role of surgery in patients with extensive or treatment-refractory disease.

Keywords : Hydatid Disease, Echinococcosis, Intra-Abdominal Hydatidosis, Hydatid Cyst, Albendazole Failure, Surgical Management.

References :

  1. WHO/OIE manual on echinococcosis in humans and animals: a public health problem of global concern, in: J. Eckert, M.A. Gemmell, F.-X. Meslin, Z. S. Pawłowski (Eds.), World Organisation for Animal Health (Office; International des Epizooties), Paris, France, and World Health Organization, Geneva: Switzerland, 2001.
  2. N. Iqbal, M. Hussain, R. Idress, M. Irfan, Disseminated hydatid cyst of liver and lung, BMJ Case Rep. 2017 (2017), bcr2017222808, https://doi.org/10.1136/bcr-2017-222808.
  3. H.O. Baba, A.M. Salih, H.O. Abdullah, et al., Primary hydatid cyst of the posterior neck; a case report with literature review, Int. J. Surg. 40 (2022) 100449, https:// doi.org/10.1016/j.ijso.2022.100449.
  4. B.L. Bairwa, A.K. Singh, S. Gupta, Laparoscopic management of giant hepatic hydatid cyst in a 12-year-old boy: a case report, J. Minim. Invasive Surg. 24 (3) (2021 Sep 15) 165–168, https://doi.org/10.7602/jmis.2021.24.3.16.
  5. R.A. Agha, T. Franchi, C. Sohrabi, G. Mathew, for the SCARE Group, The SCARE 2020 guideline: updating consensus Surgical CAse REport (SCARE) guidelines, Int J Surg. 84 (2020) 226–230.

Cystic Echinococcus is a neglected zoonotic disease caused by the larval stage of Echinococcus granulosus, commonly affecting liver and lungs and may rarely present as disseminated intra-abdominal disease with recurrent lesions despite medical therapy. We report the case of a 40-year-old male who was diagnosed with multiple intra-abdominal hydatid cysts in 2020 involving the liver, spleen, mesentery, peritoneum, and pelvis. The patient was treated with prolonged albendazole therapy and followed up regularly; however, serial imaging demonstrated persistent disease with multiple recurrences and progressive enlargement of cystic lesions. In 2026, imaging revealed a large multiloculated hydatid cyst in the right lobe of the liver with daughter cysts and focal hepatic capsular breach, along with multiple cysts in the spleen and widespread peritoneal, mesenteric, and pelvic involvement causing mass effect on adjacent structures. In view of extensive disease progression and failure to respond to medical management, the patient underwent definitive surgical intervention. This case highlights the challenges in managing disseminated hydatid disease, the potential for recurrence despite prolonged antiparasitic therapy, and the important role of surgery in patients with extensive or treatment-refractory disease.

Keywords : Hydatid Disease, Echinococcosis, Intra-Abdominal Hydatidosis, Hydatid Cyst, Albendazole Failure, Surgical Management.

Paper Submission Last Date
30 - September - 2026

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