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Fairness-Aware Melanoma Detection in Dermoscopic Images: A Deep Learning Framework with Bias Mitigation and Explainability


Authors : Arathi V. ; Harshitha N. C.; Kruthi K. Shetty; Chayadevi M. L.

Volume/Issue : Volume 11 - 2026, Issue 9 - September


Google Scholar : https://tinyurl.com/38es6a7b

DOI : https://doi.org/10.38124/ijisrt/26sep901

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Automated melanoma detection using deep learning has reached dermatologist-level accuracy on benchmark datasets, yet its clinical deployment remains constrained by a well-documented weakness: performance degrades sharply on darker skin tones because public dermoscopic archives are dominated by lighter-skinned patients. This paper presents a bias-aware, explainable framework for melanoma classification that treats data quality, subgroup fairness, and interpretability as first-class design objectives rather than post-hoc checks. Dermoscopic images drawn from the ISIC archive and the Diverse Dermatology Images (DDI) dataset are first cleaned using perceptual-hash-based duplicate removal and DullRazor-based hair/artifact suppression, then passed through a ResNet50 backbone fine-tuned via transfer learning for binary melanoma-versus-benign classification.

Keywords : Melanoma Detection; Algorithmic Fairness; Deep Learning; ResNet50; Grad-CAM; Skin Tone Bias; Dermoscopic Imaging; Explainable AI.

References :

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  2. R. Daneshjou, M. Smith, M. Sun, et al., "Lack of transparency and potential bias in artificial intelligence data sets and algorithms: A scoping review in dermatology," npj Digital Medicine, vol. 6, pp. 1–10, 2023.
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  4. M. Groh, C. Harris, R. Soenksen, et al., "Evaluating deep neural networks trained on clinical images in dermatology with diverse skin tones," Proceedings of the National Academy of Sciences (PNAS), vol. 121, no. 5, e2206834121, 2024.
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  8. K. Brinker, A. Hekler, J. S. Enk, et al., "Deep learning outperformed 136 dermatologists in a head-to-head dermoscopic melanoma image classification task," European Journal of Cancer, vol. 113, pp. 47–54, 2023.
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Automated melanoma detection using deep learning has reached dermatologist-level accuracy on benchmark datasets, yet its clinical deployment remains constrained by a well-documented weakness: performance degrades sharply on darker skin tones because public dermoscopic archives are dominated by lighter-skinned patients. This paper presents a bias-aware, explainable framework for melanoma classification that treats data quality, subgroup fairness, and interpretability as first-class design objectives rather than post-hoc checks. Dermoscopic images drawn from the ISIC archive and the Diverse Dermatology Images (DDI) dataset are first cleaned using perceptual-hash-based duplicate removal and DullRazor-based hair/artifact suppression, then passed through a ResNet50 backbone fine-tuned via transfer learning for binary melanoma-versus-benign classification.

Keywords : Melanoma Detection; Algorithmic Fairness; Deep Learning; ResNet50; Grad-CAM; Skin Tone Bias; Dermoscopic Imaging; Explainable AI.

Paper Submission Last Date
31 - October - 2026

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