Fenofibrate Solid Dispersion Method: A Review


Authors : Zahriska; Auzal Halim; danRina Wahyuni

Volume/Issue : Volume 6 - 2021, Issue 2 - February

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/37qLg71

- Fenofibrate is an effective remedy for the treatment of hypertriglycerides, hypercholesterolemia and mixed hyperlipidemia. However due to its poor water solubility fenofibrate has a poor oral absorption problem followed by low bioavalication. The manufacture of solid disperse system is a common method that can be used to increase the solubility of fenofibrate in water with the process of increasing solubility is expected to be higher fenofibrate dissolution rate. The purpose of knowing the related review of the method of making solid dispersion Fenofibrate. This review provides evidence in the literature of methods of making solid disperse fenofibrate from the year 2010- 2020. Various databases such as PubMed, ScienceDirect and Google Scholar. The search terms used are using the keywords "solid dispersion" and "fenofibrate".

Keywords : Fenofibrate, Solid Dispersion, Mission Rate.

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