Authors : Tatikonda Akshitha; Ankuri Paramesh; Pallavi Odnam; Modem Abhilash; Srinivas Chinta

Volume/Issue : Volume 11 - 2026, Issue 8 - August

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Google Scholar : https://tinyurl.com/fdx5h3re

DOI : https://doi.org/10.38124/ijisrt/26aug1296

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

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Abstract : cumulative release at 12 h. For F7, the reported kinetic fitting was highest for the Higuchi model (R² = 0.996431). On the basis of the combined physicochemical, floating and release characteristics, F7 was identified as the most suitable laboratory formulation. The findings support further investigation of ginger-extract in-situ floating gels as gastroretentive herbal delivery systems; however, botanical authentication, complete batch composition, stability, in-vivo gastric-retention studies and clinical evaluation are necessary before therapeutic or commercial claims are made.

Keywords : Ginger Extract, Gastroretentive Delivery, in-Situ Gel, Floating System, Sodium Alginate, HPMC, Sustained Release and UV–Visible Spectrophotometry.

References :

1. Gayen, S., Bandyopadhyay, R., Ganguly, R., & Das, S. (2021). A review on floating oral in-situ gelling system. International Research Journal of Modernization in Engineering Technology and Science, 3, 1816–1823.
2. Jacob, S., Mathew, A., & Shyma, M. S. (2020). A review on oral in-situ gelling system. Journal of Pharmaceutical Sciences and Research, 12, 1056–1061.
3. Aijaz, A., Subhash, V., Rageeb, M., & Kailash, R. (2019). A textbook of novel drug delivery systems. PV Publication.
4. Bevyatricks, K. J., & Joshi, A. S. (2020). Novel drug delivery systems. Pharmacy Council of India.
5. Arunachalam, A., Karthikeyan, M., & Konam, K. (2011). Floating drug delivery system: A review. International Journal of Research in Pharmaceutical Sciences, 2, 76–83.
6. Shashank, C., Prabha, K., Sunil, S., & Kumar, A. V. (2013). Approaches to increase the gastric residence time: Floating drug delivery systems—A review. Asian Journal of Pharmaceutical and Clinical Research, 6, 1–9.
7. Jassal, M., Nautiyal, U., Kundlas, J., & Singh, D. (2015). A review: Gastroretentive drug delivery system. Indian Journal of Pharmaceutical and Biological Research, 3, 82–92.
8. Parmar, P. D., Pande, S., Shan, S. H., & Sonare, N. (2014). Floating drug delivery system: A novel approach to prolong gastric retention. World Journal of Pharmaceutical and Pharmaceutical Sciences, 3, 418–444.
9. Niharika, M. G., Krishnamoorthy, K., & Akkala, M. (2018). Overview on floating drug delivery system. International Journal of Applied Pharmaceutics, 10, 65–71.