Formulation and Evaluation of Herbal Antidiabetic Tea Granules Powder


Authors : Sushant Kaluram Bhondave; Vishal S. Popade; Shantanu B. Salunke; Suyash Barve; Roshan Akotkar

Volume/Issue : Volume 10 - 2025, Issue 1 - January


Google Scholar : https://tinyurl.com/3k9npcdd

Scribd : https://tinyurl.com/2s3afj2z

DOI : https://doi.org/ 10.5281/zenodo.14891753


Abstract : The goal of the current study was to create, develop, and assess a polyherbal tea granule formulation that combined Aegle marmelos (Belpatra), Momordica charantia (Karela), Tinospora cordifolia (Guduchi), Eugenia jambolana (Jamun), and Stevia rebaudiana (Stevia) for possible antidiabetic benefits. These traditionally used herbs have all demonstrated potential as antidiabetic agents, and their combined effects may be more potent. Nine formulations (F1–F9) with varying herb quantities were made using solvent extraction, and the findings were standardized using HPLC. The optimized formulation (F5) was evaluated for its phytochemical content, antioxidant activity (DPPH, FRAP), antidiabetic activity (in vitro inhibition of α-amylase and α-glucosidase, in vivo streptozotocin-induced diabetic rats), sensory qualities (taste, aroma, color, overall acceptability), and physical attributes (moisture content, bulk density, particle size).

Keywords : Antidiabetic Activity, Herbal Tea Granules, Polyherbal Formulation, Stevia, Jamun, Karela, Guduchi, Belpatra, Phytochemical Analysis, Antioxidant Activity, Sensory Evaluation.

References :

  1. Kumar et al. (2018). Herbal remedies for diabetes management: A systematic review. Journal of Ethnopharmacology, 211, 345-355.
  2. Sharma et al. (2019). Phytochemical analysis and anti-diabetic activity of Stevia rebaudiana. Journal of Pharmaceutical Analysis, 9(2), 123-132.
  3. Singh et al. (2020). Evaluation of anti-diabetic activity of polyherbal formulation containing Gymnema, Guduchi, and Turmeric. Journal of Pharmaceutical Sciences and Research, 10(2), 133-142.2020.10.02.
  4. National diabetes statistics report, 2022. Centers for Disease Control and Prevention. Updated January 18, 2022. Accessed August 4, 2022. 
  5. Methods. National diabetes statistics report, 2022. Centers for Disease Control and Prevention. Updated September 30, 2022. Accessed November 1, 2022. 
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  13. .Khan, M. A., et al. (2018). “Antidiabetic activity of Momordica charantia and its phytochemical constituents: A review.” Frontiers in Pharmacology, 9, 691..
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The goal of the current study was to create, develop, and assess a polyherbal tea granule formulation that combined Aegle marmelos (Belpatra), Momordica charantia (Karela), Tinospora cordifolia (Guduchi), Eugenia jambolana (Jamun), and Stevia rebaudiana (Stevia) for possible antidiabetic benefits. These traditionally used herbs have all demonstrated potential as antidiabetic agents, and their combined effects may be more potent. Nine formulations (F1–F9) with varying herb quantities were made using solvent extraction, and the findings were standardized using HPLC. The optimized formulation (F5) was evaluated for its phytochemical content, antioxidant activity (DPPH, FRAP), antidiabetic activity (in vitro inhibition of α-amylase and α-glucosidase, in vivo streptozotocin-induced diabetic rats), sensory qualities (taste, aroma, color, overall acceptability), and physical attributes (moisture content, bulk density, particle size).

Keywords : Antidiabetic Activity, Herbal Tea Granules, Polyherbal Formulation, Stevia, Jamun, Karela, Guduchi, Belpatra, Phytochemical Analysis, Antioxidant Activity, Sensory Evaluation.

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