Authors : Wasayah Urooj; Husna Fatima; Dr. Shahid Mohammed

Volume/Issue : Volume 10 - 2025, Issue 2 - February

Google Scholar : https://tinyurl.com/3e3mejsu

Scribd : https://tinyurl.com/mpfxkfk8

DOI : https://doi.org/10.5281/zenodo.14965849

Abstract : Acne is one of the most common skin issues, affecting the pilosebaceous unit, primarily occurring in adolescents and adults. It mainly appears on the face but can also develop on the upper arms, trunk, and back. Hormonal changes contribute to its prevalence, with about 99.5% of teenage boys and 83% of teenage girls, which often continue throughout adolescence. The primary acne causing bacteria include Propionibacterium acnes and Staphylococcus epidermidis. Herbal formulations are gaining popularity because of their high-quality properties and minimal side effects. Herbal or herb-based medicines serve as safe alternatives using the extracts of natural origin for therapeutic benefits. The purpose of herbal therapy is to provide safe, efficient, and affordable medicines so that the people can easily access them. Additionally, these remedies contribute to skin health by providing necessary nutrients and maintaining moisture levels. The aim of this study is to formulate and evaluate an anti-acne cream with the benefits of rose, lecithin, and neem. The constituents of rose and neem showed desirable anti-acne and anti-bacterial properties and are typically used to treat acne; on the other hand, lecithin is used, which acts as a natural emulsifier and has anti-inflammatory properties. The cream was prepared by the slab technique method for mixing the cream in a geometric manner to provide a smooth texture and for mixing all ingredients properly. Specific evaluation tests are determined to confirm whether cream is appropriate for human skin, ensuring it does not cause irritation when applied.

Keywords : Acne Vulgaris; Anti-Acne Cream; Propionibacterium Acnes (P. Acne); Neem Extract.

References :

1. Choudhari nn, dudhe ar, tatter sp, zile ts, nandeshwar yk, Dhawale tp, nashine am.2023jan. Formulation and evaluation of anti-acne face cream. world journal of advanced research and reviews,19(1):1181-8.
2. Mate a, Ade p, pisé a, more s, pisé s, kharwade r.2021feb.Formulation and evaluation of polyherbal gel for the management of acne. international journal of current research and review, 13(4):117-22.
3. Muhammad Athar Abbasi, Ayesha Kausar1, Aziz-ur-Rehman, Hina Saleem, Sadia Muhammad Jahangir, Sabahat Zahra Siddiqui, and Viqar Uddin Ahmad, Preparation of new formulations of anti-acne creams and their efficacy, African Journal of Pharmacy and Pharmacology Vol. 4(6), pp. 298-303, June 2010.
4. Aditi V, Pranav s. Formulation and evaluation of topical anti-acne formulation of coriander extract. International Journal of pharmaceutical science Review and Research. 2012; 16(2): 97-103.
5. Srivastava A. Alam S, Shams S. Tiwari M, Mittal A, Sanjeev C. Formulation and evaluation of anti-acne cream containing withania somnifera Journal of pharmaceutical and scicentific Innovation.
6. Patil Priya R. (1) Patil Priyanka P. (2) Patil Rohini P. (3), Dr. Shashikant D. Barhate (4), Shaikh Samir K. (5), Formulation And Evaluation Of Multipurpose Herbal Cream Of Neem, Turmeric And Tulsi Extract, Volume 13, Issue 1 January 2025 | ISSN: 2320-2882
7. Jadhav d, Gaikwad p. formulation & evaluation of herbal anti-acne cream with antibacterial, anti-inflammatory, and anti-acne activities.
8. Luhaibi dk, Ali hh, al-ani I, shalan n, al-akayleh f, al-remawi m, nasereddin j, pinna na, al-ad hamI, Khanfar m2023oct. the formulation and evaluation of deep eutectic vehicles for the topical delivery of azelaic acid for acne treatment. molecules. 4;28(19):6927
9. Tuchayi SM, Makrantonaki E, Ganceviciene R, Dessinioti C, Feldman SR and Zouboulis CC: Acne vulgaris. Nature Reviews Disease Primers 2015; 1: 1-20.
10. Telange - Patil P.V, Nanaware P.V, Shivsharan S.P; FORMULATION AND EVALUATION OF ANTI ACNE AND ANTI OXIDENT CREAM”; International Journal of Creative Research Thought; IJCRT, Volume 10, Issue 10 October 2022 pages: 79-86.
11. Sahu T, Patel T , Sahu S, Gidwani B,“Skin Cream as Topical Drug Delivery System: A Review” Journal of   Pharmaceutical and Biological Sciences, Published by Atom and Cell Publishers, ISSN: 2320-1924.
12. Akshay Choudhary, 2Sneha Sohal, 2Kapil Kumar Verma FORMULATION AND EVALUATION OFANTIACNE FACE CREAM © 2024 IJNRD | Volume 9, Issue 10 October 2024 | ISSN: 2456-4184 | IJNRD.ORG
13. Choudhari NN, Dudhe AR, Tatte SP, Zile TS, Nandeshwar YK, Dhawale TP, et al. Formulation and evaluation of anti-acne face cream. World Journal of Advanced Research and Reviews,2023:19(1):1181–8.
14. Sharma A, Bharat Prasar. Formulation and Evaluation of herbal cosmetic cream to produce multipurpose effect on skin. Research Journal of Topical and Cosmetic Sciences,2013:4(1):1–4.
15. Aman M, Preeti M, Sapna M, Anil K. Formulation and evaluation of herbal anti acne cream. World Journal of Pharmaceutical Research,2017:6(16):589–98.
16. Chandrasekar R, Sivagami B. Formulation and Evaluation of a Poly Herbal Skin Care Cream containing Neem and Tulsi. Research Journal of Topical and Cosmetic Sciences,2018:9(1):25.
17. Navindgikar NN, Kamalapurkar KA, Chavan PS. Formulation and evaluation of multipurpose herbal cream. International Journal of Current Pharmaceutical Research,2020:12(3):25–30.
18. Arun Kumar, Divyansh, Neha Ansari, Rahul Shukla, Gangeshwar Pratap Singh,Formulation and Evaluation of Herbal Moisturizing Cream, International Journal of Pharmacy and Pharmaceutical Research; August 2022 Vol.:25, Issue:1,pages 9-16
19. Nishigandha Naresh Choudhari * , Anshu Rupesh Dudhe, Sanika Pundlik Tatte, Tanvi Sanjay Zile, Yugal Kewaldas Nandeshwar, Tanushri Pravin Dhawale and Akash Mukesh Nashine , Formulation and evaluation of anti-acne face cream, World Journal of Advanced Research and Reviews, 2023, 19(01), 1181–1188 , Article DOI: https://doi.org/10.30574/wjarr.2023.19.1.1419.
20. Mukherjee, P.K. [2002]. Quality control of herbal drugs : an approach to evaluation of botanicals business horizons.