Formulation and Evaluation of Poly Herbal Chewable Tablets from Ayurvedic Ingredients having Cough Relieving Activity


Authors : Vinayak Dasharath Gaikwad; Priyanka A. Thorat

Volume/Issue : Volume 8 - 2023, Issue 4 - April

Google Scholar : https://bit.ly/3TmGbDi

Scribd : https://bit.ly/3Bb8Inh

DOI : https://doi.org/10.5281/zenodo.7918442

In recent years, there is a spurt in the interest regarding use of Ayurvedic forms of medication. Glycyrrhiza Glabra (Liquorice), Zingiber Officinale (Ginger), Curcuma longa (Turmeric) has been used as medicine from ancient times for treating the cough. These herbal drugs use was mentioned in Ayurveda. Cough affects patients of every age, so it is the common disease condition. Because of better patient compliance, flexible design of dosage forms, ease of administration and least sterility requirements, oral route of drug administration is the well liked route. The goal of this research work is to develop Polyherbal chewable tablets of various Ayurvedic Drugs by wet granulation method and to evaluate the formulations for various pharmaceutical parameters. The purpose of this study was to produce polyherbal chewable tablets using Liquorice, Ginger, Turmeric. These polyherbal chewable tablets were formulated by technique of wet granulation method by utilizing binder that is acacia gum (5% w/v). Quality of final polyherbal chewable tablet was evaluated for pre formulation and post formulation parameter. Bulk and tapped densities, angle of repose, Carr's index, and Hausner's ratio are the preformulation tests evaluated for the prepared powder mixture (blend). Polyherbal chewable tablets were examined for general appearance, tablet size and shape, hardness, friability, weight variation as well as duration of disintegration.

Keywords : Polyherbal Chewable Tablet; Glycyrrhiza Glabr; Liquorice; Zingiber Officinal; Ginger; Curcuma longa; Turmeric; Wet granulation method; Cough; Antitussive; Demulcent; Expectorant; Cough relieving activity; Disintegration Test. I. I

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