Formulation and Evoluation of Pain Relief Balm by using Vitex Negundo and Ginger Offecinalis


Authors : Shete A.R; Sargar R.S.; Kalebhag A.M.; Dhole M.S.; Pukale A.B.; Pawar S.V.; Panaskar A.N.; Panaskar B.A.

Volume/Issue : Volume 10 - 2025, Issue 5 - May


Google Scholar : https://tinyurl.com/4paktywj

DOI : https://doi.org/10.38124/ijisrt/25may274

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Improved and new balm has a cooling effect on the skin following application. Though the amount of pressure and mobility are important factors, balms have a special pharmacological effect when it comes to pain alleviation. One of the balm’s functions is to provide a local anesthetic effect, which eventually results in comfort. It is possible to cure congestion and headaches right away, as well as aches, pains, and stiffness in the muscles, joints, feet, and stress and fatigue. In this research paper. The potential benefits of ethanolic extract of Vitex Negundo leaves in inflammatory and pain diseases have been extensively researched, While ginger oil helps with circulation, warming, and muscle relaxation because it contains bioactive compounds like gingerol. The results suggest that the combination of Vitex negundo and ginger oil offers a promising, natural alternative to synthetic pain relief formulations, with potential for further development and clinical validation.

Keywords : Pain, Vitex Negundo, Gingerol, Potential, Inflammatory.

References :

  1. Neha, B., Jannavi, R., & Sukumaran, P. (2021b). Phyto-pharmacological and BiologicalAspects of Vitex negundo Medicinal Plant – A Review. Journal of Pharmaceutical ResearchInternational, 17–32. https://doi.org/10.9734/jpri/2021/v33i29a31562
  2. Nirgundi : Benefits, precautions and dosage | 1mg. (n.d.). 1mg. https://www.1mg.com/ayurveda/nirgundi-192?srsltid=AfmBOoqmCuxDnya2T20ewSGh1%20U59CNm1TfhqzK72yT14puRHJyalhTHm&wpsrc=Google+Organic+Search
  3. Sahu, N. K. (n.d.). Development and characterized analgesic herbal balm using herbs asA medicine. GSC Advanced Research and Reviews, 19(3), 122–127. https://doi.org/10.30574/gscarr.2024.19.3.0200
  4. Sahu, N. K. (2024). Development and characterized analgesic herbal balm using herbs asA medicine. GSC Advanced Research and Reviews, 19(3), 122–127. https://doi.org/10.30574/gscarr.2024.19.3.0200
  5. Ballester, P., Cerdá, B., Arcusa, R., Marhuenda, J., Yamedjeu, K., &Zafrilla, P. (2022).Effect of ginger on inflammatory diseases. Molecules, 27(21), 7223. https://doi.org/10.3390/molecules27217223
  6. Ayustaningwarno, F., Anjani, G., Ayu, A. M., &Fogliano, V. (2024). A critical review ofGinger’s (Zingiber officinale) antioxidant, anti-inflammatory, and immunomodulatoryActivities. Frontiers in Nutrition, 11. https://doi.org/10.3389/fnut.2024.1364836
  7. Bhandare, S. D., Malode, S. S., Foxabell—LaboratoriumInvestigativum, Laboratorium scientiae et StudiorumInvestigativorum, & College of pharmacy, K.K. Wagh Institute ofEngineering Education and Research. (2024). Formulation and development of topicalNano-emulgel TDDS for delivering Vitex Negundo as a painkiller: Enhancing effectivenessWith natural essential oil permeation promoters in an innovative drug delivery system for Rheumatoid arthritis treatment—A NDDS therapeutics approach. Nano and MedicalMaterials, 4(1), 2170. https://doi.org/10.59400/nmm2170
  8. Meena, A. K., Niranjan, U. S., Yadav, A. K., Singh, B., Nagaria, A. K., Gaurav, A., & Rao, M. M. (2010). Vitex negundo Linn; a review on its ethnobotany, phytochemical and pharmacological profile. Research Journal of Pharmacognosy and Phytochemistry, 2(2), 122–128. Retrieved from https://www.i-scholar.in/index.php/Rjpp/article/view/138967
  9. sharma, K., Yadav, M., & Attri, K. (2020). Pharmacognostic studies on methanolic extract of leaves of Vitex negundo Linn. Pharmacognosy Journal, 12(3), 551–556. https://doi.org/10.5530/pj.2020.12.83
  10. Pawar, S., & Kamble, V. (2017). Phytochemical screening, elemental and functional group analysis of Vitex negundo L. leaves. International Journal of Pharmacy and Pharmaceutical Sciences, 9(6), 1–5. https://doi.org/10.22159/ijpps.2017v9i6.18093
  11. Dukre, T. P., Wadekar, G. N., Unde, A. N., & Pawar, H. B. (2023). Pharmacognostic evaluation and physicochemical screening of the rhizomes of Zingiber officinale (Ginger). Journal of Pharmacognosy and Phytochemistry, 12(5), 51–54. https://doi.org/10.22271/phyto.2023.v12.i5a.14719
  12. Fitriady, M. A., Sulaswatty, A., Agustian, E., & Salahuddin. (2017). Steam distillation extraction of ginger essential oil: Study of the effect of steam flow rate and time process. AIP Conference Proceedings, 1803(1), 030032c
  13. Thakor, H. J., Rathi, Y. S., & Nayak, N. S. (2023). Phytochemical screening of ginger (Zingiber officinale), a medicinal plant. Scholars International Journal of Traditional and Complementary Medicine, 6(4), 58–62. https://doi.org/10.36348/sijtcm.2023.v06i04.002
  14. Sahu, G. K., & Sahu, P. (2023). Development and characterization of vanishing cream. Acta Scientific Pharmaceutical Sciences, 7(6), 9–13.

Improved and new balm has a cooling effect on the skin following application. Though the amount of pressure and mobility are important factors, balms have a special pharmacological effect when it comes to pain alleviation. One of the balm’s functions is to provide a local anesthetic effect, which eventually results in comfort. It is possible to cure congestion and headaches right away, as well as aches, pains, and stiffness in the muscles, joints, feet, and stress and fatigue. In this research paper. The potential benefits of ethanolic extract of Vitex Negundo leaves in inflammatory and pain diseases have been extensively researched, While ginger oil helps with circulation, warming, and muscle relaxation because it contains bioactive compounds like gingerol. The results suggest that the combination of Vitex negundo and ginger oil offers a promising, natural alternative to synthetic pain relief formulations, with potential for further development and clinical validation.

Keywords : Pain, Vitex Negundo, Gingerol, Potential, Inflammatory.

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