Aim: Intradiploic epidermoid cysts are rare
cranial tumors, with the reports on the giant variety being
few to date. We report a case of a giant occipital
intradiploic epidermoid and review the literature on
modalities of management and outcome of giant
intradiploic epidermoids. Method: We report a 68-yearold female presenting with a giant occipital intradiploic
epidermoid. We did occipital craniectomy excising the
lesion sans the dural adhesion to the torcular region.
Postoperatively the patient had abatement of symptoms
and had an uneventful follow-up. We also reviewed the
pertinent literature on giant intradiploic epidermoids.
Results: A total of 47 cases were found, with details of the
presentation, management, and outcome available for 37
of them. Male dominance with an average of presentation
of 46 years was observed. Headache and swelling both
were equally reported as the most common symptom and
occipital bone was the most common location of the
tumor. All cases underwent craniectomy with tumor
excision and no recurrence was seen till the last follow-up
available. Conclusion: Giant intradiploic epidermoids are
rare tumors. Their clinical presentation and tumor
characteristics might be different than smaller
intradiploic epidermoids, however, they tend to carry a
good prognosis if surgical excision is attempted with
respect to the location and its proximity to venous sinuses.
Keywords : Intradiploic Epidermoid, Large Intradiploic Epidermoid, Giant Intradiploic Epidermoid.