Giant Vulvar Molluscum Pendulum a Case Report and Review of the Literature


Authors : Amal BENCHINE; Najwa LOUKILI; Rachid MAAKOUL; Samir BARGACH

Volume/Issue : Volume 9 - 2024, Issue 7 - July


Google Scholar : https://tinyurl.com/2w86atf4

Scribd : https://tinyurl.com/yedd477s

DOI : https://doi.org/10.38124/ijisrt/IJISRT24JUL1716

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background: Molluscum pendulum (MP), also known as soft fibroma, is a benign fibrous cutaneous tumor arising from mesodermal tissue. While generally small and painless, MP can become unsightly and uncomfortable as it enlarges. Giant molluscum pendulum of the vulva, a rare variant of MP, presents unique clinical challenges. The aim of this study is to present and analyze a rare case of giant molluscum pendulum (MP) of the vulva, highlighting its clinical presentation, diagnostic challenges, and treatment outcomes.  Case Presentation: We report a 51-year-old female with a progressively enlarging perineal mass over 3 years. Physical examination revealed a pedunculated mass on the left labia majora, measuring 55 x 30cm, soft, painless, and mobile. Surgical excision under general anesthesia was performed, and the resected specimen weighed 850 grams with a diameter of 5 x 3 cm. Histopathology confirmed the diagnosis of giant vulvar molluscum pendulum. The surgical margins were clear, and the patient experienced a favorable recovery with no recurrence during a one- year follow-up.  Discussion: Molluscum pendulum is a benign pedunculated skin tumor commonly found in flexion areas but rarely on the vulva. Giant vulvar molluscum pendulum is characterized by significant growth and can be mistaken for other vulvar conditions, including Bartholin’s cysts and lipomas. Accurate diagnosis through histopathological examination is crucial. While the large size of the tumor is usually benign, potential malignancy must be considered. Surgical excision remains the most effective treatment, with further management reserved for malignant cases.  Conclusion: Giant molluscum pendulum of the vulva is a rare benign tumor that can grow substantially. Accurate diagnosis and prompt surgical intervention are essential for managing this condition effectively and preventing recurrence.

Keywords : Molluscum Pendulum , Giant , Surgical Excision, Vulva.

References :

  1. E. Masson, “Molluscum pendulum atypique de l’aréole mammaire,” EM-Consulte. Accessed: Jul. 24, 2024. [Online]. Available: https://www.em-consulte.com/article/812544/resume/molluscum-pendulum-atypique-de-l-areole-mammaire
  2. “2024.S1.7.Molluscum_genital,” Our Dermatology Online. Accessed: Jul. 24, 2024. [Online]. Available: http://www.odermatol.com/issue-in-html/2024-s1-7-molluscum_genital/
  3. M. Gassama and M. Sissoko, “Molluscum pendulum géant de la vulve chez une multipare,” Pan Afr Med J, vol. 39, 2021, doi: 10.11604/pamj.2021.39.113.29582.
  4. M. El Mhadder, A. Bennis, Z. Omar, M. Benchakroun, and S. Bouabid, Molluscum Pendulum géant de la face postéro-latérale du genou : A propos d’un cas et revue de la littérature. 2024. doi: 10.13140/RG.2.2.16202.13768.
  5. F. el Hilali, S. Achkif, M. Saoud, N. Mamouni, S. Errarhay, and C. Bouchikhi, “Vulvar Fibroma (Molluscum Pendulum): Case Report,” Jan. 2021.
  6. “Molluscum Pendulum of the Areola: One Case Report,” JCRMH, Jun. 2024, doi: 10.54289/JCRMH2400139.
  7. “Surgical excision of a giant soft fibroma of the labia majora covered with a pudendal artery perforator flap - PMC.” Accessed: Jul. 28, 2024. [Online]. Available: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6976749/

Background: Molluscum pendulum (MP), also known as soft fibroma, is a benign fibrous cutaneous tumor arising from mesodermal tissue. While generally small and painless, MP can become unsightly and uncomfortable as it enlarges. Giant molluscum pendulum of the vulva, a rare variant of MP, presents unique clinical challenges. The aim of this study is to present and analyze a rare case of giant molluscum pendulum (MP) of the vulva, highlighting its clinical presentation, diagnostic challenges, and treatment outcomes.  Case Presentation: We report a 51-year-old female with a progressively enlarging perineal mass over 3 years. Physical examination revealed a pedunculated mass on the left labia majora, measuring 55 x 30cm, soft, painless, and mobile. Surgical excision under general anesthesia was performed, and the resected specimen weighed 850 grams with a diameter of 5 x 3 cm. Histopathology confirmed the diagnosis of giant vulvar molluscum pendulum. The surgical margins were clear, and the patient experienced a favorable recovery with no recurrence during a one- year follow-up.  Discussion: Molluscum pendulum is a benign pedunculated skin tumor commonly found in flexion areas but rarely on the vulva. Giant vulvar molluscum pendulum is characterized by significant growth and can be mistaken for other vulvar conditions, including Bartholin’s cysts and lipomas. Accurate diagnosis through histopathological examination is crucial. While the large size of the tumor is usually benign, potential malignancy must be considered. Surgical excision remains the most effective treatment, with further management reserved for malignant cases.  Conclusion: Giant molluscum pendulum of the vulva is a rare benign tumor that can grow substantially. Accurate diagnosis and prompt surgical intervention are essential for managing this condition effectively and preventing recurrence.

Keywords : Molluscum Pendulum , Giant , Surgical Excision, Vulva.

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