Authors : Dr. Quazi Imaduddin ; Mubasshera Sabir Khan ; Pallavi Narayan Kangare ; Abbasi Kulsum Badrey Alam ; Sayyed Ghazala Parween Abed ; Shaikh Saniya Ashokali ; Deshmukh Uneja Aslam ; Archana Laghane Sonune

Volume/Issue : Volume 10 - 2025, Issue 5 - May

Google Scholar : https://tinyurl.com/2njxm95z

DOI : https://doi.org/10.38124/ijisrt/25may649

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.

Abstract : This study investigates the potential of a novel herbal formulation combining curcumin and niacinamide for wound healing and antimicrobial activity. The formulation was developed as an antiseptic cream aimed at enhancing skin regeneration and minimizing scarring. Curcumin, known for its anti-inflammatory properties, and niacinamide, recognized for its skin barrier enhancement, were selected for their synergistic effects. The stability studies confirmed the formulation's efficacy over time, while the agar well diffusion method was employed to assess its antimicrobial activity against common pathogens. Results indicated significant wound healing properties and a reduction in scar formation, highlighting the potential of this phytochemical-rich formulation in topical therapy. This research underscores the importance of integrating traditional herbal ingredients in modern dermatological applications.

Keywords : Curcumin; Niacinamide; Wound Healing; Antimicrobial Activity; Antiseptic Cream; Herbal Formulation; Topical Therapy; Anti-Scarring; Phytochemicals; Stability Studies; Agar Well Diffusion Method.

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