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Graft Survival by Norwood-Hamilton Stage: A Stratified Outcome Analys is of Follicular Unit Extraction Patients at Vera Clinic (2020–2025)


Authors : İsmail Işık; Sait Demirci; Dr. İbrahim Alişan

Volume/Issue : Volume 11 - 2026, Issue 8 - August


Google Scholar : https://tinyurl.com/mw49sd3c

DOI : https://doi.org/10.38124/ijisrt/26aug1596

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Background: Follicular unit extraction (FUE) is now the predominant technique in surgical hair restoration, yet the relationship between severity of androgenetic alopecia (AGA), classified by the Norwood-Hamilton (NH) scale, and post-procedural graft survival has not been well characterised in adequately sized clinical cohorts. Stage-stratified survival estimates would support more precise pre-operative counselling and surgical planning.  Methods: We conducted a stratified retrospective analysis of 386 consecutive male FUE patients treated at Vera Clinic (İstanbul, Turkey) between January 2020 and December 2025, stratified by NH stage (III, III Vertex, IV, V, VI, VII). The primary outcome was graft survival rate assessed by calibrated trichoscopy at 12 months. Between-group differences were assessed by one-way ANOVA with post-hoc Tukey HSD; the stage-survival association was assessed with Spearman's rank correlation (ρ). This association was not adjusted for patient age, which co-varies with NH stage; a sensitivity analysis quantifying this co-variation is reported separately.

References :

  1. Aukerman EL, Jafferany M. The psychological consequences of androgenetic alopecia: a systematic review. J Cosmet Dermatol. 2023;22:89-95.
  2. Rassman WR, Bernstein RM, McClellan R, Jones R, Worton E, Uyttendaele H. Follicular unit extraction: minimally invasive surgery for hair transplantation. Dermatol Surg. 2002;28:720-728.
  3. Dua A, Dua K. Follicular unit extraction hair transplant. J Cutan Aesthet Surg. 2010;3(2):76-81.
  4. Kim JC, Hwang SJ, Lee JJ, Oh BM, Lee SJ, Kim DW, Kim MK. The effects of dehydration, preservation temperature and time on the hair grafts. Ann Dermatol. 2002;14(3):149-152.
  5. Norwood           OT.      Male      pattern     baldness: classification             and     incidence. South Med J. 1975;68(11):1359-1365.

Background: Follicular unit extraction (FUE) is now the predominant technique in surgical hair restoration, yet the relationship between severity of androgenetic alopecia (AGA), classified by the Norwood-Hamilton (NH) scale, and post-procedural graft survival has not been well characterised in adequately sized clinical cohorts. Stage-stratified survival estimates would support more precise pre-operative counselling and surgical planning.  Methods: We conducted a stratified retrospective analysis of 386 consecutive male FUE patients treated at Vera Clinic (İstanbul, Turkey) between January 2020 and December 2025, stratified by NH stage (III, III Vertex, IV, V, VI, VII). The primary outcome was graft survival rate assessed by calibrated trichoscopy at 12 months. Between-group differences were assessed by one-way ANOVA with post-hoc Tukey HSD; the stage-survival association was assessed with Spearman's rank correlation (ρ). This association was not adjusted for patient age, which co-varies with NH stage; a sensitivity analysis quantifying this co-variation is reported separately.

Paper Submission Last Date
31 - October - 2026

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