Authors :
Amar Makruf; Zahrah Al Jannah; Liani Dwi Fitriani; Wahyu Setia Budi; Christina Nawangsih; Eko Hidayanto; Wiwien Andriyanti; Suhadah Rabi’atul Adabiah; Edmond Rukmana Wikanta
Volume/Issue :
Volume 9 - 2024, Issue 9 - September
Google Scholar :
https://tinyurl.com/3mpvyv88
Scribd :
https://tinyurl.com/4527nkcb
DOI :
https://doi.org/10.38124/ijisrt/IJISRT24SEP1611
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Heavy metals can be found in everyday
environments and can enter the human body through
food, water, and air. Heavy metals are categorized into
three groups by the World Health Organization (WHO):
essential elements such as Copper (Cu), Chromium (Cr),
Cobalt (Co), Iron (Fe), and Zinc (Zn); potentially essential
elements like Manganese (Mn) and Nickel (Ni); and
potentially toxic elements such as Cadmium (Cd) and
Lead. (Pb). The heavy metal is a systemic poison that
causes organ dysfunction in humans. The aim of this
research is to analyze the levels of heavy metal elements
Copper (Cu), Iron (Fe), and Zinc (Zn) in the hair of breast
cancer patients. The method used to measure heavy metal
content is Inductively Coupled Plasma – Optical Emission
Spectrometry. (ICP-OES). The levels of heavy metal
elements Cu, Fe, and Zn in five hair samples from breast
cancer patients differ from the standards GBW07601 and
IAEA-086. The levels of Cu and Fe in breast cancer
patients are lower than the standard, while the level of Zn
is higher than the standard.
Keywords :
Heavy Metal, ICP-OES, Breast Cancer.
References :
- Srogi K. Analisis rambut untuk memantau polusi lingkungan dan paparan logam berat yang diakibatkannya pada manusia: Tinjauan umum. Environ. Risque Santé, (2006). 5 :391–405.
- Jaishankar, M., Tseten, T., Anbalagan, N., Mathew, B. B., & Beeregowda, K. N. Toxicity, mechanism and health effects of some heavy metals. Interdisciplinary toxicology, 7(2), (2014). 60–72.
- Tchounwou, P.B., Yedjou, C.G., Patlolla, A.K., Sutton, D.J. Heavy Metal Toxicity and the Environment. In: Luch, A. (eds) Molecular, Clinical and Environmental Toxicology. Experientia Supplementum, vol 101, (2012). Springer, Basel.
- Liu, L., Chen, J., Liu, C., Luo, Y., Chen, J., Fu, Y., Xu, Y., Wu, H., Li, X., & Wang, H. Relationships Between Biological Heavy Metals and Breast Cancer: A Systematic Review and Meta-Analysis. Frontiers in nutrition, 9, (2022). 838762.
- Morton J., Carolan VA, Gardiner PHE Penghapusan elemen yang terikat secara eksogen dari rambut manusia dengan berbagai prosedur pencucian dan penentuan dengan spektrometri massa plasma yang digabungkan secara induktif. Anal. Chim. Acta. (2002). 455 :23–34.
- Sera K., Futatsugawa S., Murao S. Analisis kuantitatif sampel rambut yang tidak diolah untuk memantau paparan logam berat pada manusia. Nucl. Instrum. Methods B. (2002). 189 :174–179.
- Fouziya, mabrouk, Samhoud., Entesar, E., Aboglida., Sameer, M., Yaseen., Ali, Emran, AL, shteewi., Saba, Z., Al-Abachi. Determination cadmium, lead and zinc in human hair by using flame atomic absorption spectrometry (faas). Journal CleanWAS, 6(1):33-36, (2022).
- Wang, T. Inductively coupled plasma optical emission spectrometry. In Ewing's Analytical Instrumentation Handbook, Fourth Edition, pp. 55-70, (2019). CRC Press.
- Florea, A. M., & Büsselberg, D. “Metals and breast cancer: risk factors or healing agents”. Journal of toxicology, (2011). 159619.
- Ankita, Rajendra, Kurup., Neena, Nair. "Copper Deficiency and Central Nervous System." International journal of zoological investigations, 08 (2022).:173-178.
- Tummala, Aarathi, Reddy., Sreevidhya, JS., K., Dolika, Prapoorna. "Iron Deficiency Anaemia in Women & Its Homoeopathic Management." International journal of research and review, 10 (2023).:35-40.
- Romaniuk, А., Lyndin, M., Sikora, V., Lyndina, Y., Romaniuk, S., & Sikora, K. Heavy metals effect on breast cancer progression. Journal of occupational medicine and toxicology (London, England), 12-32 (2017).
- Bartzatt, R. “Neurological Impact of Zinc Excess and Deficiency In Vivo”. European Journal of Nutrition & Food Safety, vol. 7, no. 3, Aug. (2017). pp. 155-60.
Heavy metals can be found in everyday
environments and can enter the human body through
food, water, and air. Heavy metals are categorized into
three groups by the World Health Organization (WHO):
essential elements such as Copper (Cu), Chromium (Cr),
Cobalt (Co), Iron (Fe), and Zinc (Zn); potentially essential
elements like Manganese (Mn) and Nickel (Ni); and
potentially toxic elements such as Cadmium (Cd) and
Lead. (Pb). The heavy metal is a systemic poison that
causes organ dysfunction in humans. The aim of this
research is to analyze the levels of heavy metal elements
Copper (Cu), Iron (Fe), and Zinc (Zn) in the hair of breast
cancer patients. The method used to measure heavy metal
content is Inductively Coupled Plasma – Optical Emission
Spectrometry. (ICP-OES). The levels of heavy metal
elements Cu, Fe, and Zn in five hair samples from breast
cancer patients differ from the standards GBW07601 and
IAEA-086. The levels of Cu and Fe in breast cancer
patients are lower than the standard, while the level of Zn
is higher than the standard.
Keywords :
Heavy Metal, ICP-OES, Breast Cancer.