Histological Subtype of Renal Cell Tumors at Urology Department of Teaching Hospital Hassan 2, Morocco


Authors : Mohammed Mzyiene; Mustapha Ahsaini; Ouima Justin Dieudonné Ziba; Soufiane Mellas; Jalal Eddine El ammari; Mohammed Fadl Tazi; Mohammed Jamal El fassi; Mohammed Sekal; Taoufiq Harmouch; Moulay Hassan Farih

Volume/Issue : Volume 6 - 2021, Issue 5 - May

Google Scholar : http://bitly.ws/9nMw

Scribd : https://bit.ly/3hUIr3T

The aim of this study is the analysis of the anatomopathological aspects of renal tumors in our center. Materials and methods this is a retrospective study of 108 cases of renal tumors collected from the Department of Urology CHU HASSAN II FES and Department of Anatomy - Pathology CHU HASSAN II FES over 10 years from 2009 to 2019. Results There were 108 patients, 65 men, and 43 women, the median age was 59 years with a range of age between 30 years and 85 years. Most of our patients had presented urologic signs at the time of the diagnosis, which was dominated by low back pain (47%) and hematuria (22%). The left kidney was affected in 56.3% of cases and the right kidney in 42.7% of cases. The average height is 7 cm with extremes of 2 and 9.5. Tumors of heterogeneous appearance represent the majority of cases with a percentage of 52.4% of which 40% is encapsulated and 12% without capsule, buffyellow tumors is 22.3% with the presence of capsule in 17.4%, whitish 20% of which 19.4% are encapsulated. Histologically, papillary carcinoma was found in 17.5% of cases and chromophobic cell carcinoma was noted in 10.9% of cases. Low-grade mucinous tubular spindle cell carcinoma and angiomyolipoma were reported in our study (2.7%), (4.6%), carcinosarcoma in 2.78% of cases, carcinoid tumor in 0, 93% of cases, and oncocytoma 1.58%. For histo-prognostic factors, Fuhrman's grade 2 was the most frequently revealed in 44% of cases followed by grade 3 in 33%. For the pTNM classification, the stage pT2 was predominant followed by pT1, lymph node involvement was found in 13% of cases and metastases in 12%. The outcome was favorable in 81% and unfavorable in 19%.

Keywords : Renal Cell Carcinoma, Subtypes of Renal Cell Carcinoma, Immunohistochemistry of Renal Cell Carcinoma, Staging, Classification of Renal Cell Carcinoma

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