Authors :
Vishwa S. Patel; Jaydeep J. Gajjar; Tirth B. Patel; Aryan V. Patel; Mona A. Gupta
Volume/Issue :
Volume 8 - 2023, Issue 3 - March
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://bit.ly/3LT72Vn
DOI :
https://doi.org/10.5281/zenodo.7894575
Abstract :
Karl Meyer and his assistant John Palmer
first found hyaluronic acid (HA), a biopolysaccharide
with a high molecular weight, in the vitreous of cows'
eyes in 1934. In addition to humans, microorganisms
have major biological uses for hyaluronic acid. This
review discusses hyaluronic acid's clinical applications,
basic pharmacological properties, various physiological
and pathological activities, and metabolisms. In addition
to being present in most connective tissues, it is notably
concentrated in umbilical cords, chicken combs, synovial
fluid, and the vitreous fluid of the eye. Hyaluronan
synthases, a type of integral membrane proteins,
produce it in nature, while hyaluronidases are the
enzymes that break it down.
Keywords :
History, Metabolism, Toxicity, Properties, Structure, Application.
Karl Meyer and his assistant John Palmer
first found hyaluronic acid (HA), a biopolysaccharide
with a high molecular weight, in the vitreous of cows'
eyes in 1934. In addition to humans, microorganisms
have major biological uses for hyaluronic acid. This
review discusses hyaluronic acid's clinical applications,
basic pharmacological properties, various physiological
and pathological activities, and metabolisms. In addition
to being present in most connective tissues, it is notably
concentrated in umbilical cords, chicken combs, synovial
fluid, and the vitreous fluid of the eye. Hyaluronan
synthases, a type of integral membrane proteins,
produce it in nature, while hyaluronidases are the
enzymes that break it down.
Keywords :
History, Metabolism, Toxicity, Properties, Structure, Application.
