Authors :
Athmeek K. P; Asha Yohannan; Rosmy Wilson
Volume/Issue :
Volume 10 - 2025, Issue 4 - April
Google Scholar :
https://tinyurl.com/z7jkr9v6
Scribd :
https://tinyurl.com/3567f66h
DOI :
https://doi.org/10.38124/ijisrt/25apr1033
Google Scholar
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Abstract :
This paper explores the identification of unlisted aromatic compounds in cold rub formulations through simple,
cost-effective qualitative chemical tests. Acetone is employed as a solvent for sample preparation, and methods such as the
iodine, sulfuric acid, and potassium permanganate tests are used to detect aromatic compounds. The study’s findings
validate the hypothesis that these compounds can be identified using chemical testing, laying the foundation for future
research and regulatory practices to ensure consumer safety.
Keywords :
Inhalants, Cold Rubs.
References :
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- CalABDEF, K., & SopalaBDF, M. (2008). Ex vivo skin absorption of terpenes from Vicks VapoRub® ointment. Med Sci Monit, 14(8), 23. https://ppm.gumed.edu.pl/docstore/download/@GUM56c2efe7ec2543dfb4114a9f10c54c57/0000045945.pdf
- Smith, M. L., Nichols, D. C., Underwood, P., Fuller, Z., Moser, M. A., Flegel, R., Gorelick, D. A., Newmeyer, M. N., Concheiro, M., & Huestis, M. A. (2014). Methamphetamine and amphetamine isomer concentrations in human urine following controlled Vicks VapoInhaler administration. Journal of Analytical Toxicology, 38(8), 524–527. https://doi.org/10.1093/jat/bku077
- Yadav, P. K., Panesar, A., & Sharma, R. M. (2020). Analysis of some commonly found inhalants using gas chromatography-mass spectrometry (GC MS) – Effect of substrates on the identification of inhalants. Science & Justice, 61(1), 61–71. https://doi.org/10.1016/j.scijus.2020.09.003
- Smith, A., & Matthews, O. (2022). Aromatic ointments for the common cold: what does the science say? Drugs in Context, 11, 1–9. https://doi.org/10.7573/dic.2022-5-6
- Paz-Ramos, M. I., Cruz, S. L., & Violante-Soria, V. (2023). Amphetamine-type stimulants: novel insights into their actions and use patterns. Revista de investigación clínica, 75(3), 143-157. https://doi.org/10.24875/ric.23000110
- Fulga, A., Zenovia, A., Ene, D. C., Stan, C., Firescu, D., & Fulga, I. (2021, November 18). Addiction to nasal Decongestants based on Α-Adrenoceptor Agonists case series and literature review EuroEconomica.https://www.ceeol.com/search/article-detail?id=1017846
- Balster, R. L., Cruz, S. L., Howard, M. O., Dell, C. A., & Cottler, L. B. (2009). Classification of abused inhalants. Addiction, 104(6), 878–882.
- https://doi.org/10.1111/j.1360-0443.2008.02494.x
- Grover, S., Kumar, S., Kulhara, P., Mattoo, S., Basu, D., Biswas, P., & Shah, R. (2008). Inhalant abuse: A clinic-based study. Indian Journal of Psychiatry, 50(2), 117. https://doi.org/10.4103/0019-5545.42399
- Suchita, G., Smita, T., Sahil, M., Harshada, S., Kalpesh, M., & Pallavi, G. (2024). HERBAL INHALATION PODS FOR NASAL DECONGESTION. Degrés, 9(4). https://degres.eu/wp-content/uploads/8-DEJ1271.pdf
This paper explores the identification of unlisted aromatic compounds in cold rub formulations through simple,
cost-effective qualitative chemical tests. Acetone is employed as a solvent for sample preparation, and methods such as the
iodine, sulfuric acid, and potassium permanganate tests are used to detect aromatic compounds. The study’s findings
validate the hypothesis that these compounds can be identified using chemical testing, laying the foundation for future
research and regulatory practices to ensure consumer safety.
Keywords :
Inhalants, Cold Rubs.