⚠ Official Notice: www.ijisrt.com is the official website of the International Journal of Innovative Science and Research Technology (IJISRT) Journal for research paper submission and publication. Please beware of fake or duplicate websites using the IJISRT name.



Impact of Health Literacy on Medication Adhernce and Outcomes in Progressive Syringomyelia: A Case Report


Authors : Mabuto Michelle Tanaka; Praveena Sathisetti

Volume/Issue : Volume 11 - 2026, Issue 3 - March


Google Scholar : https://tinyurl.com/9u9x7zzb

Scribd : https://tinyurl.com/4wpxtfna

DOI : https://doi.org/10.38124/ijisrt/26mar1194

Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.


Abstract : Syringomyelia is a progressive degenerative disorder characterized by formation of a fluid-filled cavity (syrinx) in the spinal cord, which leads to different neurological dysfunctions. The case describes a 54-year-old female agricultural labourer who presented with a history of chronic back pain and progressive neurological symptoms. Her symptoms began five years earlier following a fall while carrying heavy loads during work. Initially, she experienced persistent back pain and sought medical care, where analgesic medications were prescribed. Due to inadequate relief, she later pursued homeopathic treatment for 2 -3 years without improvement. She went to another hospital with complaints of reeling sensation for 15 days, chronic lower back pain for 1-year, bilateral lower limb pain associated with heaviness, difficulty rising from a sitting position, and occasional knuckle pain. Laboratory investigations revealed haemoglobin of 11 g/dL, MCV 77 FL, MCH 23.2 pg, MCHC 30.1 g/dL, and ESR 58 mm/hour. An MRI demonstrated herniation of bilateral cerebellar tonsils 7 mm below the foramen magnum and a focal syrinx at the C6–C7 level. Additionally, disc desiccation and diffuse annular bulges were noted at L3–L5 levels with thecal sac indentation and bilateral neural foraminal narrowing compressing exiting nerve roots. Based on the above findings, a diagnosis of syringomyelia was established. The patient was managed with gabapentin nortriptyline, methyl cobalamin, and calcium vitamin D3. This case highlights the importance of early diagnosis, patient education, and timely neuro-rehabilitation. A multidisciplinary approach plays a vital role in improving patient treatment outcomes.

Keywords : Syringomyelia, Magnetic Resonance Imaging (MRI), Neuro-Rehabilitation, Patient Counselling, Treatment Plan.

References :

  1. Heiss JD, PN, DeVroom HL, et al: Elucidating the pathophysiology of syringomyelia. J Neurosurg 91:553-562, 1999 doi.org/10.3171/jns.1999.91.4.0553
  2. Milhorat TH, Capocelli AL Jr, Anzil AP, et al: Pathological basis of spinalcord cavitation in syringomyelia: analysis of 105 autopsy cases. J Neuosurg 82:802-812, 1995 doi.org/10.3171/jns.1995.82.5.0802
  3. Milhorat TH, Chou MW, Trinidad EM, et al: Chiari I malformation redefined: clinical and radiographic findings for 364 symptomatic patients. Neurosurgery 44(5): p 1005-1017, May 1999.
  4. Zheng YC, Liu YT, Wei KC, Huang YC, Chen PY, Hsu YH, Lin CL. Outcome predictors and clinical presentation of syringomyelia. Asian J Surg. 2023 Feb;46(2): 705-711.doi.org/10.1016/j.asjsur.2022.06.150
  5. Milhorat TH, Capocelli AL, Anzil AP, Kotzen RM, Milhorat RH. Pathological basis of spinal cord cavitation in syringomyelia: analysis of 105 autopsy cases. J Neurosurg. 1995 May;82(5): 802-12.doi.org/10.3171/jns.1995.82.5.0802
  6. Ciaramitaro P, Garbossa D, Peretta P, Piatelli G, Massimi L, Valentini L, Migliaretti G, Baldovino S, Roccatello D, Kodra Y, Taruscio D., Interregional Chiari and Syringomyelia Consortium. on behalf of the Interregional Chiari and Syringomyelia Consortium. Syringomyelia and Chiari Syndrome Registry: advances in epidemiology, clinical phenotypes and natural history based on a North Western Italy cohort. Ann Ist Super Sanita. 2020 Jan-Mar;56(1):48-58. doi.org/10.3171/jns.1995.82.5.0802
  7. Roy AK, Slimack NP, Ganju A. Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management. Neurosurg Focus. 2011 Dec;31(6): E15. [PubMed] [Reference list], Klekamp J, Batzdorf U, Samii M, Bothe HW. Treatment of syringomyelia associated with arachnoid scarring caused by arachnoiditis or trauma. J Neurosurg. 1997 Feb;86(2):233-40. doi.org/10.3171/2011.9. FOCUS11198
  8. Michals EA, Ramsey RG: Syringomyelia. Orthop Nurs. 1996, 15:33-40. Greitz D: Unraveling the riddle of syringomyelia. Neurosurg Rev. 2006, 29:251-264. 10.1007/s101430060029-5 doi.org/10.1007/s10143-006-0029-5
  9. Ciaramitaro P, Garbossa D, Peretta P, Piatelli G, Massimi L, Valentini L, Migliaretti G, Baldovino S, Roccatello D, Kodra Y, Taruscio D., Interregional Chiari and Syringomyelia Consortium. on behalf of the Interregional Chiari and Syringomyelia Consortium. Syringomyelia and Chiari Syndrome Registry: advances in epidemiology, clinical phenotypes and natural history based on a North Western Italy cohort. Ann Ist Super Sanita. 2020 Jan-Mar;56(1):48-58.
  10. Syringomyelia Workup Updated: Apr 17, 2023Author: Hassan Ahmad Hassan Al-Shatoury, MD, PhD, MHPE;
  11. Flint G: Syringomyelia: diagnosis and management. Pract Neurol. 2021, 21:403-411. 10.1136/practneurol 2021-002994 doi.org/10.1136/practneurol-2021-002994
  12. Syringomyelia Workup Updated: Apr 17, 2023Author: Hassan Ahmad Hassan Al-Shatoury, MD, PhD, MHPE;
  13. Shenoy VS, Munakomi S, Sampath R. Syringomyelia. [Updated 2024 Mar 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.
  14. Roy AK, Slimack NP, Ganju A. Idiopathic syringomyelia: retrospective case series, comprehensive review, and update on management. Neurosurg Focus. 2011 Dec;31(6): E15.doi.org/10.3171/2011.9. FOCUS11198
  15. Shenoy VS, Munakomi S, Sampath R. Syringomyelia. [Updated 2024 Mar 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2026 Jan-.
  16. Ciaramitaro P, Garbossa D, Peretta P, Piatelli G, Massimi L, Valentini L, Migliaretti G, Baldovino S, Roccatello D, Kodra Y, Taruscio D., Interregional Chiari and Syringomyelia Consortium. on behalf of the Interregional Chiari and Syringomyelia Consortium. Syringomyelia and Chiari Syndrome Registry: advances in epidemiology, clinical phenotypes and natural history based on a North Western Italy cohort. Ann Ist Super Sanita. 2020 Jan-Mar;56(1):48-58.
  17. Guan J, Yuan C, Zhang C, Ma L, Yao Q, Cheng L, Liu Z, Wang K, Duan W, Wang X, Wu H, Chen Z, Jian F. Intradural Pathology Causing Cerebrospinal Fluid Obstruction in Syringomyelia and Effectiveness of Foramen Magnum and Foramen of Magendie Dredging Treatment. World Neurosurg. 2020 Dec;144: e178-e188. doi.org/10.1016/j.wneu.2020.08.068
  18. Mora, J.R., Rison, R.A. & Beydoun, S.R. Chiari malformation type I with cervicothoracic syringomyelia masquerading as bibrachial amyotrophy: a case report. J Med Case Reports 9, 11 (2015). doi.org/10.1186/1752-1947-9-11
  19. Güler-Uysal, F., Orkun, S., Cila, A. et al. Delayed post-traumatic syringohydromyelia after an uncomplicated fracture of the spine: Case report and literature review. Spinal Cord 34, 301–304 (1996) doi.org/10.1038/sc.1996.55
  20. Colombo A, Cislaghi MG. Familial syringomyelia: case report and review of the literature. Ital J Neurol Sci. 1993 Dec;14(9):637-9. doi: 10.1007/BF02339249. PMID: 8125767.
  21. Mora, J.R., Rison, R.A. & Beydoun, S.R. Chiari malformation type I with cervicothoracic syringomyelia masquerading as bibrachial amyotrophy: a case report. J Med Case Reports 9, 11 (2015). doi.org/10.1186/1752-1947-9-11
  22. Nivedha V. Kannapadi, Safwan O. Alomari, Giorgio Caturegli, et al: Management of syringomyelia associated with tuberculous meningitis: A case report and systematic review of the literature doi.org/10.1016/j.jocn.2021.01.052

Syringomyelia is a progressive degenerative disorder characterized by formation of a fluid-filled cavity (syrinx) in the spinal cord, which leads to different neurological dysfunctions. The case describes a 54-year-old female agricultural labourer who presented with a history of chronic back pain and progressive neurological symptoms. Her symptoms began five years earlier following a fall while carrying heavy loads during work. Initially, she experienced persistent back pain and sought medical care, where analgesic medications were prescribed. Due to inadequate relief, she later pursued homeopathic treatment for 2 -3 years without improvement. She went to another hospital with complaints of reeling sensation for 15 days, chronic lower back pain for 1-year, bilateral lower limb pain associated with heaviness, difficulty rising from a sitting position, and occasional knuckle pain. Laboratory investigations revealed haemoglobin of 11 g/dL, MCV 77 FL, MCH 23.2 pg, MCHC 30.1 g/dL, and ESR 58 mm/hour. An MRI demonstrated herniation of bilateral cerebellar tonsils 7 mm below the foramen magnum and a focal syrinx at the C6–C7 level. Additionally, disc desiccation and diffuse annular bulges were noted at L3–L5 levels with thecal sac indentation and bilateral neural foraminal narrowing compressing exiting nerve roots. Based on the above findings, a diagnosis of syringomyelia was established. The patient was managed with gabapentin nortriptyline, methyl cobalamin, and calcium vitamin D3. This case highlights the importance of early diagnosis, patient education, and timely neuro-rehabilitation. A multidisciplinary approach plays a vital role in improving patient treatment outcomes.

Keywords : Syringomyelia, Magnetic Resonance Imaging (MRI), Neuro-Rehabilitation, Patient Counselling, Treatment Plan.

Paper Submission Last Date
31 - March - 2026

SUBMIT YOUR PAPER CALL FOR PAPERS
Video Explanation for Published paper

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe