Authors :
Nishat Amique; Dr. A. K. Sinha; Dr. Najmul Hason; Alisha Khurshid
Volume/Issue :
Volume 7 - 2022, Issue 11 - November
Google Scholar :
https://bit.ly/3IIfn9N
Scribd :
https://bit.ly/3Gs7IPa
DOI :
https://doi.org/10.5281/zenodo.7334244
Abstract :
The use of Sunscreens has been increasing
over the last few decades, its awareness among general
masses as protector from cancer, wrinkles, dark spot
and tanning of skin are being emerged as one of the
foremost basis of greater than before use of sunscreen.
Primarily exposure to sunlight is the main source of
biosynthesis of vitamin D in lower epidermal layer of
skin where UVB rays photolyze provitamin D (
Synthesized from 7- hydrocholestrol ) to previtamin D.
Unfortunately dietary sources of vitamin D is very
scarce. The richest source is fatty fishes ( Tuna, Meckrel
and salmon ) and fish liver oil whereas lesser amounts
are found in egg yolks, cheese and beef liver. This study
was designed to find out the impact of sunscreen on
biosynthesis of vitamin D in females who were recently
diagnosed as hypoivitaminosis D patients in different
clinics. The total 213 newly diagnosed patients of
hypovitaminosis D were given questionnaire to get their
feed back about the regular use of sunscreen
formulations. Out of 213 subjects 159 ( 74.64%, having
vitamin level in serum within a range of 3.69 to 11.48
ng/ml ) were regularly using sunscreen and only 54 (
25.35% having a range between 9.27 to 18.93 ng/ml )
patients were found as intermittent user. The ratio of
subjects covertly indicative that sunscreen (mostly SPF
15 and 30) may slow down the biosynthesis of Vitamin D
by blocking the UVB rays. Further studies with larger
sample size would be required for better interpretation.
Keywords :
7- hydrocholesterol, Sunscreen, Previtamin D, Provitamin D, 25-hydroxyvitamin D3.
The use of Sunscreens has been increasing
over the last few decades, its awareness among general
masses as protector from cancer, wrinkles, dark spot
and tanning of skin are being emerged as one of the
foremost basis of greater than before use of sunscreen.
Primarily exposure to sunlight is the main source of
biosynthesis of vitamin D in lower epidermal layer of
skin where UVB rays photolyze provitamin D (
Synthesized from 7- hydrocholestrol ) to previtamin D.
Unfortunately dietary sources of vitamin D is very
scarce. The richest source is fatty fishes ( Tuna, Meckrel
and salmon ) and fish liver oil whereas lesser amounts
are found in egg yolks, cheese and beef liver. This study
was designed to find out the impact of sunscreen on
biosynthesis of vitamin D in females who were recently
diagnosed as hypoivitaminosis D patients in different
clinics. The total 213 newly diagnosed patients of
hypovitaminosis D were given questionnaire to get their
feed back about the regular use of sunscreen
formulations. Out of 213 subjects 159 ( 74.64%, having
vitamin level in serum within a range of 3.69 to 11.48
ng/ml ) were regularly using sunscreen and only 54 (
25.35% having a range between 9.27 to 18.93 ng/ml )
patients were found as intermittent user. The ratio of
subjects covertly indicative that sunscreen (mostly SPF
15 and 30) may slow down the biosynthesis of Vitamin D
by blocking the UVB rays. Further studies with larger
sample size would be required for better interpretation.
Keywords :
7- hydrocholesterol, Sunscreen, Previtamin D, Provitamin D, 25-hydroxyvitamin D3.
