Authors :
Dr. P. S. Eswar; Dr. Zulekha Bhimani; Dr. Pednekar; Dr. Mehnish Malik; Dr. Nidhi Shah
Volume/Issue :
Volume 10 - 2025, Issue 3 - March
Google Scholar :
https://tinyurl.com/53szm7hy
Scribd :
https://tinyurl.com/6zt5huwa
DOI :
https://doi.org/10.38124/ijisrt/25mar324
Note : A published paper may take 4-5 working days from the publication date to appear in PlumX Metrics, Semantic Scholar, and ResearchGate.
Abstract :
Introduction:
Pancreatic pseudocysts represent a significant complication of pancreatitis, occurring as encapsulated collections of
pancreatic fluid surrounded by fibrous or granulation tissue. While the incidence of pancreatitis is well-documented
globally, the development of pseudocysts and their risk factors requires further investigation.
Methods:
A prospective clinical study was conducted at Dr. D.Y. Patil University, School of Medicine, from November 2021 to
November 2022. The study included 100 patients above 18 years with confirmed pancreatitis diagnosis. Initial
ultrasonography was performed upon admission, with follow-up imaging scheduled after six weeks. The study analyzed
demographic factors, risk factors, and clinical outcomes.
Results:
The study revealed a 25% overall incidence of pancreatic pseudocysts, with significant gender disparity (34% in males
vs. 16% in females, p=0.038). Gallstone disease emerged as a significant risk factor (p=0.020), particularly in males (60%
incidence, p=0.002). The highest pseudocyst development rates were observed in acute necrotizing pancreatitis (80%) and
acute on chronic pancreatitis (54.5%). History of ERCP showed significant correlation with pseudocyst formation (55.6%,
p=0.026). Complications were minimal, with only 2% showing pressure effects and no mortality reported.
Keywords :
Pancreatic Pseudocyst, Pancreatitis, Gallstone Disease, Acute Necrotizing Pancreatitis, Risk Factors, Incidence Study, Ultrasonography, Clinical Outcomes, Gender Disparity, ERCP Complications.
References :
- Banks PA, Bollen TL, Dervenis C, et al. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013;62(1):102-111.
- Forsmark CE, Vege SS, Wilcox CM. Acute Pancreatitis. N Engl J Med. 2016;375(20):1972-1981.
- Tyberg A, Karia K, Gabr M, et al. Management of pancreatic fluid collections: A comprehensive review of the literature. World J Gastroenterol. 2016;22(7):2256-2270.
- Zhao K, Adam SZ, Keswani RN, et al. Acute Pancreatitis: Revised Atlanta Classification and the Role of Cross-Sectional Imaging. AJR Am J Roentgenol. 2015;205(1):W32-41.
- Sarr MG, Banks PA, Bollen TL, et al. The new revised classification of acute pancreatitis 2012. SurgClin North Am. 2013;93(3):549-562.
- Cui ML, Kim KH, Kim HG, et al. Incidence, risk factors and clinical course of pancreatic fluid collections in acute pancreatitis. Dig Dis Sci. 2014;59(5):1055-1062.
- Dhaka N, Samanta J, Kochhar S, et al. Pancreatic fluid collections: What is the ideal imaging technique? World J Gastroenterol. 2015;21(48):13403-13410.
- vanSantvoort HC, Bakker OJ, Bollen TL, et al. A conservative and minimally invasive approach to necrotizing pancreatitis improves outcome. Gastroenterology. 2011;141(4):1254-1263.
- Zerem E, Hauser G, Loga-Zec S, et al. Minimally invasive treatment of pancreatic pseudocysts. World J Gastroenterol. 2015;21(22):6850-6860.
- Andalib I, Dawod E, Kahaleh M. Modern Management of Pancreatic Fluid Collections. J Clin Med. 2018;7(4):E54.
- Kim KO, Kim TN. Acute pancreatic pseudocyst: incidence, risk factors, and clinical outcomes. Pancreas. 2012;41(4):577-581. doi:10.1097/MPA.0b013e3182374def
- Lerch MM, Stier A, Wahnschaffe U, Mayerle J. Pancreatic pseudocysts: observation, endoscopic drainage, or resection?. DtschArztebl Int. 2009;106(38):614-621. doi:10.3238/arztebl.2009.0614
- Imrie CW, Buist LJ, Shearer MG. Importance of cause in the outcome of pancreatic pseudocysts. Am J Surg. 1988;156(3 Pt 1):159-162. doi:10.1016/s0002-9610(88)80055-2
- Maringhini A, Uomo G, Patti R, et al. Pseudocysts in acute nonalcoholic pancreatitis: incidence and natural history. Dig Dis Sci. 1999;44(8):1669-1673. doi:10.1023/a:1026691700511.
Introduction:
Pancreatic pseudocysts represent a significant complication of pancreatitis, occurring as encapsulated collections of
pancreatic fluid surrounded by fibrous or granulation tissue. While the incidence of pancreatitis is well-documented
globally, the development of pseudocysts and their risk factors requires further investigation.
Methods:
A prospective clinical study was conducted at Dr. D.Y. Patil University, School of Medicine, from November 2021 to
November 2022. The study included 100 patients above 18 years with confirmed pancreatitis diagnosis. Initial
ultrasonography was performed upon admission, with follow-up imaging scheduled after six weeks. The study analyzed
demographic factors, risk factors, and clinical outcomes.
Results:
The study revealed a 25% overall incidence of pancreatic pseudocysts, with significant gender disparity (34% in males
vs. 16% in females, p=0.038). Gallstone disease emerged as a significant risk factor (p=0.020), particularly in males (60%
incidence, p=0.002). The highest pseudocyst development rates were observed in acute necrotizing pancreatitis (80%) and
acute on chronic pancreatitis (54.5%). History of ERCP showed significant correlation with pseudocyst formation (55.6%,
p=0.026). Complications were minimal, with only 2% showing pressure effects and no mortality reported.
Keywords :
Pancreatic Pseudocyst, Pancreatitis, Gallstone Disease, Acute Necrotizing Pancreatitis, Risk Factors, Incidence Study, Ultrasonography, Clinical Outcomes, Gender Disparity, ERCP Complications.