Authors :
Manpreet Kaur; Vishwajeet Singh Bumrah
Volume/Issue :
Volume 8 - 2023, Issue 5 - May
Google Scholar :
https://bit.ly/3TmGbDi
Scribd :
https://tinyurl.com/3s94s85f
DOI :
https://doi.org/10.5281/zenodo.8031806
Abstract :
Manipulating fungi to enhance the yield of
industrially important products is a fairly common
practice and methods to do so are increasingly improving
to maximize the yield of the product more than the
presently used methods. Fungi form competent hosts for
such manipulations and procedures because of their
smaller genome sizes that can be studied and exploited for
various research and industrial endeavors. This technique
is commonly known to improve the regulation of lipid
metabolism, production of fermentation products,
heterologous proteins and genome evolutionary editing in
Saccharomyces cerevisiae, Aspergillus sp., Rhizopus sp.,
Mucor sp. and Mortierella alpina.
Keywords :
gene editing techniques; CRISPR/Cas9; Aspergillus oryzae; Aspergillus niger; Saccharomyces cerevisiae; Ogataea thermomethanolica; Rhizopus arrhizus; Mucor circinelloides; Mortierella alpina; heterologous protein production; lipid metabolism; fermentation products; evolutionary engineering; transformation.
Manipulating fungi to enhance the yield of
industrially important products is a fairly common
practice and methods to do so are increasingly improving
to maximize the yield of the product more than the
presently used methods. Fungi form competent hosts for
such manipulations and procedures because of their
smaller genome sizes that can be studied and exploited for
various research and industrial endeavors. This technique
is commonly known to improve the regulation of lipid
metabolism, production of fermentation products,
heterologous proteins and genome evolutionary editing in
Saccharomyces cerevisiae, Aspergillus sp., Rhizopus sp.,
Mucor sp. and Mortierella alpina.
Keywords :
gene editing techniques; CRISPR/Cas9; Aspergillus oryzae; Aspergillus niger; Saccharomyces cerevisiae; Ogataea thermomethanolica; Rhizopus arrhizus; Mucor circinelloides; Mortierella alpina; heterologous protein production; lipid metabolism; fermentation products; evolutionary engineering; transformation.
