Authors :
Chetan D. Tangade; J.V. Vyas; Dr. V.V. Paithankar; Dr. A.M. Wankhade
Volume/Issue :
Volume 9 - 2024, Issue 1 - January
Google Scholar :
http://tinyurl.com/28m9dfx6
Scribd :
http://tinyurl.com/87bu53ed
DOI :
https://doi.org/10.5281/zenodo.10613097
Abstract :
These issues can be successfully avoided with
injectable hydrogels by releasing medication locally at
the tumor site. The benefits of local toxicity on the tumor
have prompted studies into whether hydrogels are
appropriate for drug delivery. Different hydrogel drug
delivery systems, such as heat-, pH-, light-, and dual-
sensitive hydrogels, have been developed in accordance
with different cancer types and stages. Recent
developments in hydrogels and other drug delivery
technologies are highlighted in this review. In conclusion,
as we learn more about injectable hydrogels for cancer
treatment at a site, their efficacy and durability as
treatments improve. Promising avenues for future
research include smart delivery systems that react
differently to stimuli at different times based on
alterations in the tumor site's microenvironment.
Because there are numerous polymer systems to choose
from that have diverse chemical properties and excellent
performance,there has been an increase in interest in
Injectable hydrogels have been used in cancer therapy in
recent years.To address the shortcomings of the
available treatments, several research teamsare
developing ablation systems appropriate for thermal and
photothermal ablation, radiation therapy, and
chemotherapyThe initial polymers' structure and
properties are frequently categorized by origin or
syntheticity—are the main topics of our work, which
reviews and discusses the most recent developments in
injectable hydrogel technology.
Keywords :
Polyphosphazenes (PPZ), Camptotechin (CPT), Tumor Cell Lysates 3 (TLR3), Nanocapsule-Based Hydrogels (NBL), Blood-Brain Barrier (BBB), Doxorubicin (DOX).
These issues can be successfully avoided with
injectable hydrogels by releasing medication locally at
the tumor site. The benefits of local toxicity on the tumor
have prompted studies into whether hydrogels are
appropriate for drug delivery. Different hydrogel drug
delivery systems, such as heat-, pH-, light-, and dual-
sensitive hydrogels, have been developed in accordance
with different cancer types and stages. Recent
developments in hydrogels and other drug delivery
technologies are highlighted in this review. In conclusion,
as we learn more about injectable hydrogels for cancer
treatment at a site, their efficacy and durability as
treatments improve. Promising avenues for future
research include smart delivery systems that react
differently to stimuli at different times based on
alterations in the tumor site's microenvironment.
Because there are numerous polymer systems to choose
from that have diverse chemical properties and excellent
performance,there has been an increase in interest in
Injectable hydrogels have been used in cancer therapy in
recent years.To address the shortcomings of the
available treatments, several research teamsare
developing ablation systems appropriate for thermal and
photothermal ablation, radiation therapy, and
chemotherapyThe initial polymers' structure and
properties are frequently categorized by origin or
syntheticity—are the main topics of our work, which
reviews and discusses the most recent developments in
injectable hydrogel technology.
Keywords :
Polyphosphazenes (PPZ), Camptotechin (CPT), Tumor Cell Lysates 3 (TLR3), Nanocapsule-Based Hydrogels (NBL), Blood-Brain Barrier (BBB), Doxorubicin (DOX).