Authors : Dr. Saima Muhammed Nawaz; Jabin Abdulla Modatheeri; Nuzhat Nawaz

Volume/Issue : Volume 10 - 2025, Issue 7 - July

Google Scholar : https://tinyurl.com/53s82xnv

DOI : https://doi.org/10.38124/ijisrt/25jul106

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Abstract : This case study investigates the impact of Lyme neuroborreliosis (LNB) on cognitive and executive functions in a 60- year-old pilot. Using purposive sampling, the participant’s executive function was assessed with the Delis-Kaplan Executive Function System (D-KEFS), and memory was evaluated with the Wechsler Memory Scale (WMS). A quantitative approach employing paired with t-tests compared to cognitive performance before and after LNB diagnosis. Results showed a significant decline in memory function post-LNB (t (3) = 3.055, p = 0.028). Executive function also declined, particularly in visual scanning and inhibition, although these changes were not statistically significant (t (2) = 2.079, p = 0.087). These findings suggest that LNB may contribute to cognitive deterioration, especially in memory domains. The rapid cognitive decline observed within six months from superior to below-average performance highlights the aggressive progression of Lyme neuroborreliosis on cognitive function especially in memory. This swift deterioration underscores the urgent need for early and comprehensive cognitive assessments to enable timely intervention and support. Given the study limitation of a single participant and no control group, further research with larger samples is necessary. Comprehensive cognitive assessments are recommended for individuals with LNB to facilitate timely intervention and support.

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