Investigation of Potentially Toxic Elements (PTEs) Concentrations in Natural and Synthetic Product Cosmetics Used in Lagos, Nigeria


Authors : Christian Aloysius; Olusegun John-Dewole; Ozioma Juliana Anekwe; Benjamin Izuchukwu Nwabueze

Volume/Issue : Volume 9 - 2024, Issue 5 - May

Google Scholar : https://tinyurl.com/47c8w4cz

Scribd : https://tinyurl.com/5t5xkhfb

DOI : https://doi.org/10.38124/ijisrt/IJISRT24MAY682

Abstract : The use of cosmetics in their various forms has been historical and still trending. Potentially toxic elements (PTEs) have been found to be critical constituents of these cosmetics, though as either functional ingredients or as impurities. This has raised health concerns such as; in kidney failures, heart diseases and birth defects. This study investigate the presence and levels of certain indexed PTEs in both natural and synthetic cosmetics and their associated health implications on users in Lagos State, Nigeria. Three natural product cosmetics namely; palm kernel oil (PKO), shear butter and ‘tiro’ labelled as NC1, NC2 and NC3 respectively, and five brands of synthetic product cosmetics (SPCs) labelled as SC1, SC2, SC3, SC4 and SC5 were selected for analysis based on questionnaire response to cosmetic use among Badagry women. The metal analysis done using ICPOES showed that NC3 is PTEs laden; Mn (38.132 + 8.195) ppm, Ni (42.04 + 2.331) ppm, Pb (65.341 + 3.064) and Zn (92.89 + 6.62) ppm. Mn concentration is the highest amongst all the SPCs, ranging from 17.56 + 2.09 ppm to 29.04 + 0.012 ppm. Ni concentration ranged from 0.506 + 0.073 ppm to 9.88 + 1.43 ppm. The presence of these PTEs could be attributed to unintended contamination from raw material or product processing, or deliberately added as part of the required ingredients as in the case of some synthetic cosmetics. The level of PTEs in the synthetic cosmetics were below the permissible limits set by WHO. However, the risk of bioaccumulation exists due to continuous use over time.

Keywords : Cosmetics, ICPOES, Kohl, Metal bio-intake, PTEs, Toxicity.

References :

  1. Chan, T., Chan, A., & Tang, H. Nephrotic Syndrome Caused by Exposures to Skin-lightening Cosmetic Products Containing Inorganic Mercury. Clinical Toxicology 1, 2019, 7 – 8.
  2. Ajaezi, G.C., Amadi, C.N., Ekhator, O.C., Igbiri, S., & Orisakwe, O.E. Cosmetic use in Nigeria may be safe: a human health risk assessment of metals and metalloids in some common brands. Journal of Cosmetic Science, 69(6), 2018, 429-445.
  3. Ghaderpoori, M., Kamarehie, B., Jafari, A., Alinejad, A.A., Hashempour, Y., Saghi, M.H.,  Yousefi, M., Oliveri, G., Mohammadi, A.A., Ghaderpoury, A., & Ferrante, M. Health risk assessment of heavy metals in cosmetic products sold in Iran: the Monte Carlo simulation. Environmental Science and Pollution Research, 27, 2020, pp.7588-7595.
  4. Kilic, S., Kilic, M., & Soylak, M. The determination of toxic metals in some traditional cosmetic products and health risk assessment. Biol Trace Elem Res. 2020, 1–6.
  5. Agorku, E. Mercury and Hydroquinone Content of Skin Toning Creams and Cosmetic Soaps, and the Potential Risks to the Health of Ghanaian Women. Springerplus, 5, 2016, 319.
  6. McMichael, J.R., & Stoff, B.K. Surma eye cosmetic in Afghanistan: a potential source of lead toxicity in children. European journal of pediatrics, 177(2), 2018, 265-268.
  7. Alam, M.F., Akhter, M., Mazumder, B., Ferdous, A., Hossain, M.D., Dafader, N.C., & Ullah, A.A. Assessment of some heavy metals in selected cosmetics commonly used in Bangladesh and human health risk. Journal of Analytical Science and Technology, 10(1), 2019, 1-8.
  8. Aldayel, O., Hefne, J., Alharbi, K.N., & Al-Ajyan, T. Heavy metals concentration in facial cosmetics. Nat Prod Chem Research, 6:2018, 303.
  9. Health Canada. Toxic Metals Found in Make-up Cosmetics. A report released by Environmental Defence, 2011, 24 – 26.
  10. Al-Qutob, M., Alatrash, M., & Abol-ola, S. Determination of different heavy metals concentrations in cosmetics purchased from Palestinian markets by ICP/MS. Bioflux, 5(3):2013, 287-293.
  11. Al-Saleh I., & Al-Doush, I. Mercury Content in Skin Lightening Creams and Potential Hazards to the Health of Saudi Women. J Toxicol Environ Health 51, 2, 1997, 123 – 130.
  12. Anton, G., Weyland, W., & Nater, J.  Unwanted Effects of Cosmetics and Drugs used in Dermatology. Netherlands: Elsevier, 2005, 422 – 423.
  13. Arshad, H., Mehmood, M.Z., Shah, M.H., & Abbasi, A.M. Evaluation of heavy metals in cosmetic products and their health risk assessment. Saudi Pharmaceutical Journal, 28(7), 2020, 779-790.
  14. Li, H., Zheng, J., Wang, H., Huang, G., Huang, Q., Feng, N., & Xiao, J. Maternal cosmetics use during pregnancy and risks of adverse outcomes: a prospective cohort study. Scientific reports, 9(1), 2019, 80-30.
  15. Bruce, S. A., Christensen, K. Y., Coons, M. J., Havlena, J. A., Meiman, J. G., & Walsh, R. O. Using Medicaid Data to Improve Childhood Lead Poisoning Prevention Program Outcomes and Blood Lead Surveillance. Journal of Public Health Management and Practice, 25, 2019, 51-57.
  16. Sprinkle, R. Leaded Eye Cosmetics: A Cultural Cause of Elevated Lead Levels in Children. Journal of Family Practice 40, 4, 1995, 358 – 359.
  17. Spungen, J.H. Children’s exposures to lead and cadmium: FDA total diet study 2014–16. Food Addit. Contam. 36, 2019, 893–903.
  18. Sangoremi, A.A. and Hamilton-Amachree, A. Elemental Composition and Proximate analysis of Shea Butter Sold in Swali Market, Yenegoa, Nigeria. Intl Journal of Env. Agric and Biotech. 6(1), 2021, 236-240.
  19. Sani, A. Gaya, M. and Abubakar, F. Determination of Some Heavy Metals in Selected Cosmetic Products Sold in Kano Metropolis, Nigeria. Toxicology Reports 3, 2016, 866 – 867.
  20. Nnorom, I. Igwe, J. & Oji-Nnorom, C. Trace Metal Contents of Facial (Make-up) Cosmetics Commonly used in Nigeria. African Journal of Biotechnology, 4, 2005, 1133.
  21. Omenka, S. & Adeyi, A. Heavy Metal Content of Selected Personal Care Products (PCPs) Available in Ibadan, Nigeria and their Toxic Effects. Toxicology reports 3, 2016, 628 – 630.
  22. Oyelakin, V., Saidykhan, V., Secka, P., Adjivon, A., & Acquaye, H.B.  Assessment of the Level of Mercury Present in Soaps by the use of Cold Vapour Atomic Flourescence Spectrometric Analysis – A Gambian Case Study. Ethiopian Journal of Environmental Studies and Measurement 3, 8, 2010, 8 – 12.
  23. Bilal, M., & Iqbal, H.M. An insight into toxicity and human-health-related adverse consequences of cosmeceuticals a review. Science of the total environment, 670:2019, 555-568.
  24. Fowler, J., Woolery-Loyd, H., Waldorf, H., & Saini, R. Innovations in Natural Ingredients and their use in Skin Care.  J Drugs Dermatol, 9, 2010, 72.
  25. García, J.D.D., & Arceo, E. Renal damage associated with heavy metals: review work. Revista Colombiana de Nefrología, 5(1), 2018, 45-53.
  26. Chauhan, A. ,Bhadauria, R., Singh, A., Lodhi, S., Chaturvedi, D., & Tomar, V. Determination of Lead and Cadmium in Cosmetic Products. Journal of Chemical and Pharmaceutical Research, 2, 2010, 92 – 95.
  27. Dayan, A., & Paine, A. Mechanisms of Chromium Toxicity, Carcinogenicity and Allergenicity: Review of the literature from 1985 to 2000. Human and Experimental Toxicology, 20, 2001, 439 – 451.
  28. Emmanuel, A., & Oluwasanni, D. Evaluating Heavy Metals in Toning Creams using the Wet Acid and Dry Ashing Method. Journal of Chemical sciences, 1, 2019, 1.
  29. Gowhar, S.A. Harmful effects of beauty care products on human health. International Journal of Medical Science and Public Health, 7(1), 2018, 1-9.
  30. Omolaoye, J.A.,  Uzairu, A. & Gimba, C.E Heavy Metals Assessment of Some Eye Shadow Products Imported to Nigeria from China. Archives of Applied Science Research 2, 2010, 76 – 84.
  31. Oyedeji, F.O., Hassan, G.O., & Adeleke, B.B. Hydroquinone and Heavy Metals Levels in Cosmetics Marketed in Nigeria. Trends in Applied Science Research, 6, 2011, 622 – 639

The use of cosmetics in their various forms has been historical and still trending. Potentially toxic elements (PTEs) have been found to be critical constituents of these cosmetics, though as either functional ingredients or as impurities. This has raised health concerns such as; in kidney failures, heart diseases and birth defects. This study investigate the presence and levels of certain indexed PTEs in both natural and synthetic cosmetics and their associated health implications on users in Lagos State, Nigeria. Three natural product cosmetics namely; palm kernel oil (PKO), shear butter and ‘tiro’ labelled as NC1, NC2 and NC3 respectively, and five brands of synthetic product cosmetics (SPCs) labelled as SC1, SC2, SC3, SC4 and SC5 were selected for analysis based on questionnaire response to cosmetic use among Badagry women. The metal analysis done using ICPOES showed that NC3 is PTEs laden; Mn (38.132 + 8.195) ppm, Ni (42.04 + 2.331) ppm, Pb (65.341 + 3.064) and Zn (92.89 + 6.62) ppm. Mn concentration is the highest amongst all the SPCs, ranging from 17.56 + 2.09 ppm to 29.04 + 0.012 ppm. Ni concentration ranged from 0.506 + 0.073 ppm to 9.88 + 1.43 ppm. The presence of these PTEs could be attributed to unintended contamination from raw material or product processing, or deliberately added as part of the required ingredients as in the case of some synthetic cosmetics. The level of PTEs in the synthetic cosmetics were below the permissible limits set by WHO. However, the risk of bioaccumulation exists due to continuous use over time.

Keywords : Cosmetics, ICPOES, Kohl, Metal bio-intake, PTEs, Toxicity.

Never miss an update from Papermashup

Get notified about the latest tutorials and downloads.

Subscribe by Email

Get alerts directly into your inbox after each post and stay updated.
Subscribe
OR

Subscribe by RSS

Add our RSS to your feedreader to get regular updates from us.
Subscribe